Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine storms (CSs) are …

The intestinal epithelium has one of the highest rates of cellular turnover in a process that is
tightly regulated. As the transit-amplifying progenitors of the intestinal epithelium generate …

Mixed lineage kinase domain-like (MLKL) is the terminal protein in the pro-inflammatory
necroptotic cell death program. RIPK3-mediated phosphorylation is thought to initiate MLKL …

Over the past 15 years, elegant studies have demonstrated that in certain conditions,
programed cell death resembles necrosis and depends on a unique molecular pathway with …

Regulated cell death has essential functions in development and in adult tissue
homeostasis. Necroptosis is a newly discovered pathway of regulated necrosis that requires …

Necroptosis is a form of regulated cell death, which is induced by ligand binding to TNF
family death domain receptors, pattern recognizing receptors and virus sensors. The …

Cell death is a fundamental process in cardiac pathologies. Recent studies have revealed
multiple forms of cell death, and several of them have been demonstrated to underlie …

Background Unraveling the mystery of cell death is one of the most fundamental progresses
of life sciences during the past decades. Regulated cell death (RCD) or programmed cell …

The intestinal epithelium constitutes an indispensable single-layered barrier to protect the
body from invading pathogens, antigens or toxins. At the same time, beneficial nutrients and …

Plastics are novel environmental pollutants with potential threats to the ecosystem. At least
5.25 trillion plastic particles in the environment, of which nanoplastics are< 100 nm in …