miRNAs as cornerstones in colorectal cancer pathogenesis and resistance to therapy: A spotlight on signaling pathways interplay—A review

MA Elrebehy, S Al-Saeed, S Gamal, A El-Sayed… - International journal of …, 2022 - Elsevier
Colorectal cancer (CRC) is the world's third most prevalent cancer and the main cause of
cancer-related mortality. A lot of work has been put into improving CRC patients' clinical …

From strings to signals: Unraveling the impact of miRNAs on diagnosis, and progression of colorectal cancer

OA Mohammed - Pathology-Research and Practice, 2023 - Elsevier
Colorectal cancer (CRC) stands as the third most prevalent ailment globally and represents
the primary cause of mortality associated with cancer. Significant advancements have been …

Molecular functions of microRNAs in colorectal cancer: recent roles in proliferation, angiogenesis, apoptosis, and chemoresistance

DES Ellakwa, N Mushtaq, S Khan, A Jabbar… - Naunyn-Schmiedeberg's …, 2024 - Springer
MiRNAs (microRNAs) constitute a group of diminutive molecules of non-coding RNA
intricately involved in regulating gene expression. This regulation is primarily accomplished …

miR‑146b‑5p promotes colorectal cancer progression by targeting TRAF6

L Shi, Y Su, Z Zheng, J Qi… - Experimental and …, 2022 - spandidos-publications.com
Increasing evidence highlights the multiple roles of microRNAs (miRs) in the tumorigenesis
of colorectal cancer (CRC); however, the molecular mechanism, particularly the target of …

Prognostic value of expression levels of miR‑148a, miR‑152 and HLA‑G in colon cancer

L Emirzeoglu, O Olmez… - Oncology …, 2022 - spandidos-publications.com
Aberrant expression of human leukocyte antigen G (HLA‑G), an immunosuppressive
molecule, has been observed in various cancer types. The exact mechanism of HLA‑G …

A review on interplay between small RNAs and oxidative stress in cancer progression

A Das, H Ganesan, S Sriramulu, F Marotta… - Molecular and Cellular …, 2021 - Springer
Oxidative stress has been known to be the underlying cause in many instances of cancer
development. The new aspect of cancer genesis that has caught the attention of many …

A novel miRNA‐based signature as predictive tool of survival outcome of colorectal cancer patients

B Zhao, W Wang, H Ye, J Wang… - Chemical Biology & …, 2023 - Wiley Online Library
It is great significance of identifying valuable biomarkers for early diagnosis and prognostic
prediction of colorectal cancer (CRC) patients. This study aimed at developing and …

Association between miRNA-499 gene polymorphism and autoimmune diseases: A meta-analysis

X Kong, S Diao, H Xu, J Sun, B Ma - Plos one, 2022 - journals.plos.org
Introduction The association between miRNA-499 rs3746444 and a variety of autoimmune
diseases has been reported. However, these results were contradictory and just focused on …

结直肠癌和高脂饮食关系的研究进展及其防治对策

徐文晖, 卞京, 郑磊贞 - 上海交通大学学报(医学版), 2021 - xuebao.shsmu.edu.cn
结直肠癌(colorectal cancer, CRC) 是世界范围内五大恶性肿瘤之一, 其发病率位居恶性肿瘤第
三, 死亡率位居第二, 严重威胁着人类的生命健康. 流行病学研究显示, 经济发达国家的CRC …

Tumor Suppressor MicroRNAs in Clinical and Preclinical Trials for Neurological Disorders

A Lui, T Do, O Alzayat, N Yu, S Phyu, HJ Santuya… - Pharmaceuticals, 2024 - mdpi.com
Cancers and neurological disorders are two major types of diseases in humans. We
developed the concept called the “Aberrant Cell Cycle Disease (ACCD)” due to the …