Single-cell analysis reveals diversity of tumor-associated macrophages and their interactions with T lymphocytes in glioblastoma

S Batchu, KA Hanafy, N Redjal, SS Godil… - Scientific Reports, 2023 - nature.com
Glioblastoma (GBM) is an aggressive primary CNS malignancy and clinical outcomes have
remained stagnant despite introduction of new treatments. Understanding the tumor …

Immune checkpoints represent a promising breakthrough in targeted therapy and prognosis of myelodysplastic syndrome

X Guo, S Yu, X Ren, L Li - Heliyon, 2023 - cell.com
Myelodysplastic syndrome (MDS) is a hematological malignancy of undetermined etiology,
possibly linked to chromosomal structural alterations, genetic mutations, presentation and …

Immunotherapeutic targeting of surfaceome heterogeneity in AML

ME Bordeleau, É Audemard, A Métois, L Theret, V Lisi… - Cell Reports, 2024 - cell.com
Immunotherapy remains underexploited in acute myeloid leukemia (AML) compared to other
hematological malignancies. Currently, gemtuzumab ozogamicin is the only therapeutic …

[HTML][HTML] Prognostic Analysis of Lactic Acid Metabolism Genes in Oral Squamous Cell Carcinoma

S Shen, H Zhang, Y Qian, X Zhou, J Li, L Zhang… - International Dental …, 2024 - Elsevier
Objectives Oral squamous cell carcinoma (OSCC) is the most common malignant tumour in
the oral and maxillofacial region. Lactic acid accumulation in the tumour microenvironment …

Chemotherapy resistance in acute myeloid leukemia is associated with decreased anti-tumor immune response through MHC molecule and B7 family members

J Ge, X Yin, X Sun, L Kou, X Xue, J Ma - Discover Oncology, 2024 - Springer
Acute myeloid leukemia (AML) remains challenging due to chemotherapeutic drug-
resistance (CDR). Aberrant expression B7 family proteins are involved in tumors evasion …

T cell exhaustion: Supremacy in leukemia as for disease and therapy

NK Mohamed, MA El-Mokhtar… - Bulletin of …, 2024 - bpsa.journals.ekb.eg
In this review, an overview of exhausted T cells in acute and chronic leukemias including
myelocytic and lymphoblastic leukemia was made to browse this important subset of cells …