Cannabidiol (CBD), the main nonpsychoactive constituent of Cannabis sativa, has shown a
wide range of therapeutically promising pharmacological effects either as a sole drug or in …

Cannabidiol (CBD) has been traditionally used in Cannabis-based preparation, however
historically, it has received far less interest as a single drug than the other components of …

INTRODUCTION Infection causes inflammation, which contributes to pathogen clearance
and organismal survival. The balance between the intensity and resolution of an …

Cannabidiol is a class of non-psychoactive plant cannabinoids derived from cannabis
plants. Currently, Epidiolex (Cannabidiol) has been approved by the FDA for the treatment of …

Spurred by a growing interest in cannabidiolquinone (CBDQ, HU-313, 2) as a degradation
marker and alledged hepatotoxic metabolite of cannabidiol (CBD, 1), we performed a …

Different studies about the anticancer potential of several medically used antibacterial
fluoroquinolones have been established. Fluoroquinolone derivatives, like some anti …

Fluoroquinolones are a class of widely prescribed antibiotics with a broad range of activity
against Gram-positive, Gram-negative, and some atypical microbes. Unfortunately, these …

A cannabinoid anticancer para-quinone, HU-331, which was synthesized by our group five
decades ago, was shown to have very high efficacy against human cancer cell lines in-vitro …

In the late 1980s, reports emerged describing experimental antibacterial quinolones having
significant potency against eukaryotic Type II topoisomerases (topo II) and showing cytotoxic …

Type II DNA topoisomerases resolve topological knots and tangles in DNA that result from
routine cellular processes and are effective targets for anticancer therapeutics. To this end …