The gastrointestinal tract is the only internal organ to have evolved with its own independent
nervous system, known as the enteric nervous system (ENS). This Review provides an …

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …

Abstract Serotonin (5-HT) has been recognized for decades as an important signalling
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …

Abstract Mitochondrial uncoupling protein 1 (UCP1) is enriched within interscapular brown
adipose tissue (iBAT) and beige (also known as brite) adipose tissue,, but its thermogenic …

Repair of defective hard-tissues in osteoporotic patients faces significantly challenges with
limited therapeutic options. Although biomedical cements are considered promising …

The past 15 years have witnessed tremendous progress in the molecular understanding of
osteoblasts, the main bone-forming cells in the vertebrate skeleton. In particular, all of the …

Numerous tissue regeneration paradigms show evident neurological dependence, including
mammalian fingertip, skin, and bone regeneration. The mature skeleton is innervated by an …

The gut microbiota modulates host metabolism and development of immune status. Here we
show that the gut microbiota is also a major regulator of bone mass in mice. Germ‐free (GF) …

The gut microbiota (GM) is the whole of commensal, symbiotic, and pathogenic
microorganisms living in our intestine. The GM–host interactions contribute to the maturation …

5-Hydroxytryptamine (serotonin) in the gastrointestinal trac... : Current Opinion in
Endocrinology, Diabetes and Obesity 5-Hydroxytryptamine (serotonin) in the …