The human intestine contains an intricate ecological community of dwelling bacteria,
referred as gut microbiota (GM), which plays a pivotal role in host homeostasis. Multiple …

The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …

Intestinal immune homeostasis and microbiome structure play a critical role in the
pathogenesis and progress of inflammatory bowel disease (IBD), whereas IBD treatment …

A key challenge for the effective treatment of gastrointestinal diseases including
inflammatory bowel disease is to develop an orally administered drug delivery system …

Chitosan is the polymer of choice for delivery of the active moieties to the colon due to its
cationic nature that enables strong mucosal attachment. Chitosan is explored for …

Colon targeted drug delivery systems have gained a great deal of attention as potential
carriers for the local treatment of colonic diseases with reduced systemic side effects and …

The therapeutic outcomes of oral nanomedicines against colon cancer are heavily
compromised by their lack of specific penetration into the internal tumor, favorable anti …

As naturally occurring bioactive products, several lines of evidence have shown the potential
of polyphenols in the medical intervention of various diseases, including tumors …

Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …