Sepsis represents the host's systemic inflammatory response to a severe infection. It causes
substantial human morbidity resulting in hundreds of thousands of deaths each year …

Septic shock, the most severe complication of sepsis, is a deadly disease. In recent years,
exciting advances have been made in the understanding of its pathophysiology and …

Objective: To quantify the accuracy of serum procalcitonin as a diagnostic test for sepsis,
severe sepsis, or septic shock in adults in intensive care units or after surgery or trauma …

Objective: To decide whether the use of blood lactate monitoring in critical care practice is
appropriate. We performed a systematic health technology assessment as blood lactate …

Background A number of biomarkers have been studied for the diagnosis of sepsis in
paediatrics, but no gold standard has been identified. Procalcitonin (PCT) was demonstrated …

Context.—Sepsis, affecting millions of individuals annually with an associated high mortality
rate, is among the top 10 causes of death. In addition, improvements in diagnostic tests for …

BACKGROUND Serum microRNAs (miRNAs) can be used as biomarkers for many kinds of
diseases, and some are even better than current indicators. The aim of this study was to …

Sepsis is a major healthcare problem from the perspective of mortality and economics.
Advances in diagnostic detection of infection and sepsis have been slow, but recent …

Objective: to investigated the circulating microRNA expression profile in sepsis and its
clinical evaluation. Methods: 70 patients with sepsis and 30 patients with SIRS were …

Sepsis is a major challenge in medicine. It is a common and frequently fatal infectious
condition. The incidence continues to increase, with unacceptably high mortality rates …