Serial sampling of serum protein biomarkers for monitoring human traumatic brain injury dynamics: a systematic review

EP Thelin, FA Zeiler, A Ercole, S Mondello… - Frontiers in …, 2017 - frontiersin.org
Background The proteins S100B, neuron-specific enolase (NSE), glial fibrillary acidic
protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light …

Diffuse axonal injury and oxidative stress: a comprehensive review

A Frati, D Cerretani, AI Fiaschi, P Frati, V Gatto… - International journal of …, 2017 - mdpi.com
Traumatic brain injury (TBI) is one of the world's leading causes of morbidity and mortality
among young individuals. TBI applies powerful rotational and translational forces to the …

Utility of neuron-specific enolase in traumatic brain injury; relations to S100B levels, outcome, and extracranial injury severity

EP Thelin, E Jeppsson, A Frostell, M Svensson… - Critical care, 2016 - Springer
Background In order to improve assessment and outcome prediction in patients suffering
from traumatic brain injury (TBI), cerebral protein levels in serum have been suggested as …

Biomarkers for the clinical differential diagnosis in traumatic brain injury—a systematic review

S Yokobori, K Hosein, S Burks, I Sharma… - CNS neuroscience & …, 2013 - Wiley Online Library
Rapid triage and decision‐making in the treatment of traumatic brain injury (TBI) present
challenging dilemma in “resource poor” environments such as the battlefield and developing …

The prognostic value of serum neuron-specific enolase in traumatic brain injury: systematic review and meta-analysis

F Cheng, Q Yuan, J Yang, W Wang, H Liu - PloS one, 2014 - journals.plos.org
Background Several studies have suggested that neuron-specific enolase (NSE) in serum
may be a biomarker of traumatic brain injury. However, whether serum NSE levels correlate …

Recommendations for the critical care management of devastating brain injury: prognostication, psychosocial, and ethical management: a position statement for …

MJ Souter, PA Blissitt, S Blosser, J Bonomo, D Greer… - Neurocritical care, 2015 - Springer
Devastating brain injuries (DBIs) profoundly damage cerebral function and frequently cause
death. DBI survivors admitted to critical care will suffer both intracranial and extracranial …

Diffuse axonal injury: epidemiology, outcome and associated risk factors

RCA Vieira, WS Paiva, DV De Oliveira… - Frontiers in …, 2016 - frontiersin.org
Diffuse axonal injury (DAI), a type of traumatic injury, is known for its severe consequences.
However, there are few studies describing the outcomes of DAI and the risk factors …

What's new in traumatic brain injury: update on tracking, monitoring and treatment

C Reis, Y Wang, O Akyol, WM Ho… - International journal of …, 2015 - mdpi.com
Traumatic brain injury (TBI), defined as an alteration in brain functions caused by an external
force, is responsible for high morbidity and mortality around the world. It is important to …

Factors contributing to outcome following traumatic brain injury

J Ponsford - NeuroRehabilitation, 2013 - content.iospress.com
Background: Traumatic brain injury results in some distinctive patterns of cognitive,
behavioural and physical impairment which impact significantly on independent living skills …

Blood biomarkers in moderate-to-severe traumatic brain injury: potential utility of a multi-marker approach in characterizing outcome

AP Di Battista, JE Buonora, SG Rhind… - Frontiers in …, 2015 - frontiersin.org
Background Blood biomarkers are valuable tools for elucidating complex cellular and
molecular mechanisms underlying traumatic brain injury (TBI). Profiling distinct classes of …