Structure and dynamics of interfacial peptides and proteins from vibrational sum-frequency generation spectroscopy

S Hosseinpour, SJ Roeters, M Bonn, W Peukert… - Chemical …, 2020 - ACS Publications
Proteins at interfaces play important roles in cell biology, immunology, bioengineering, and
biomimetic material design. Many biological processes are based on interfacial protein …

Self-assembled peptide nanostructures for functional materials

MS Ekiz, G Cinar, MA Khalily, MO Guler - Nanotechnology, 2016 - iopscience.iop.org
Nature is an important inspirational source for scientists, and presents complex and elegant
examples of adaptive and intelligent systems created by self-assembly. Significant effort has …

Toward understanding bacterial ice nucleation

M Lukas, R Schwidetzky, RJ Eufemio… - The Journal of …, 2022 - ACS Publications
Bacterial ice nucleators (INs) are among the most effective ice nucleators known and are
relevant for freezing processes in agriculture, the atmosphere, and the biosphere. Their …

Elevated concentrations cause upright alpha-synuclein conformation at lipid interfaces

SJ Roeters, K Strunge, KB Pedersen… - Nature …, 2023 - nature.com
The amyloid aggregation of α-synuclein (α S), related to Parkinson's disease, can be
catalyzed by lipid membranes. Despite the importance of lipid surfaces, the 3D-structure and …

Sub-nanometer mapping of the interfacial electric field profile using a vibrational stark shift ruler

D Bhattacharyya, PE Videla, JM Palasz… - Journal of the …, 2022 - ACS Publications
The characterization of electrical double layers is important since the interfacial electric field
and electrolyte environment directly affect the reaction mechanisms and catalytic rates of …

Ice-nucleating proteins are activated by low temperatures to control the structure of interfacial water

SJ Roeters, TW Golbek, M Bregnhøj, T Drace… - Nature …, 2021 - nature.com
Ice-nucleation active (INA) bacteria can promote the growth of ice more effectively than any
other known material. Using specialized ice-nucleating proteins (INPs), they obtain nutrients …

Misfolding of a human islet amyloid polypeptide at the lipid membrane populates through β-sheet conformers without involving α-helical intermediates

J Tan, J Zhang, Y Luo, S Ye - Journal of the American Chemical …, 2019 - ACS Publications
Amyloid formation has been implicated in many fatal diseases, but its mechanism remains to
be clarified due to a lack of effective methods that can capture the transient intermediates …

The dysferlin C2A domain binds PI (4, 5) P2 and penetrates membranes

E Kwok, SC Otto, P Khuu, AP Carpenter… - Journal of Molecular …, 2023 - Elsevier
Dysferlin is a large membrane protein found most prominently in striated muscle. Loss of
dysferlin activity is associated with reduced exocytosis, abnormal intracellular Ca2+ and the …

Interfacial water ordering is insufficient to explain ice-nucleating protein activity

M Lukas, R Schwidetzky, AT Kunert… - The Journal of …, 2020 - ACS Publications
Ice-nucleating proteins (INPs) found in bacteria are the most effective ice nucleators known,
enabling the crystallization of water at temperatures close to 0° C. Although their function …

Heterodyne-detected achiral and chiral vibrational sum frequency generation of proteins at air/water interface

M Okuno, T Ishibashi - The Journal of Physical Chemistry C, 2015 - ACS Publications
We present complex achiral and chiral vibrational sum frequency generation (VSFG) spectra
at the air/water interface of protein solutions by using heterodyne-detected VSFG. Bovine …