A longitudinal big data approach for precision health

SM Schüssler-Fiorenza Rose, K Contrepois… - Nature medicine, 2019 - nature.com
Precision health relies on the ability to assess disease risk at an individual level, detect early
preclinical conditions and initiate preventive strategies. Recent technological advances in …

[HTML][HTML] A high triglyceride-glucose index is associated with left ventricular dysfunction and atherosclerosis

TH Chiu, HJ Tsai, HYC Chiou, PY Wu… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Background: The triglyceride-glucose (TyG) index has been reported to be a simple and
reliable surrogate marker of insulin resistance. The aim of this study was to investigate …

Association of non-alcoholic fatty liver disease with left ventricular changes in treatment-naïve patients with uncomplicated hypertension

C Catena, G Brosolo, A Da Porto, D Donnini… - Frontiers in …, 2022 - frontiersin.org
Background and aims Cardiac structural and functional changes have been demonstrated in
patients with non-alcoholic fatty liver disease (NAFLD). Because of the frequent association …

Impact of insulin resistance on subclinical left ventricular dysfunction in normal weight and overweight/obese Japanese subjects in a general community

K Hirose, K Nakanishi, M Daimon, N Sawada… - Cardiovascular …, 2021 - Springer
Background Insulin resistance carries increased risk of heart failure, although the
pathophysiological mechanisms remain unclear. LV global longitudinal strain (LVGLS) …

Risk of cardiovascular events associated with pathophysiological phenotypes of type 2 diabetes

JV Stidsen, DH Christensen… - European Journal of …, 2022 - academic.oup.com
Objective Hyperglycaemia in type 2 diabetes is caused by varying degrees of two defects:
low insulin sensitivity and beta-cell dysfunction. We assessed if subgrouping of patients into …

Extracellular vesicles and insulin resistance: A potential interaction in vascular dysfunction

T Sáez, F Toledo, L Sobrevia - Current Vascular Pharmacology, 2019 - ingentaconnect.com
Insulin resistance plays a key role in cardiovascular complications associated with diabetes
mellitus and hypertensive disorders. In states of insulin resistance several circulating factors …

Association between the triglyceride–glucose index and left ventricular global longitudinal strain in patients with coronary heart disease in Jilin Province, China: a …

L Na, W Cui, X Li, J Chang, X Xue - Cardiovascular Diabetology, 2023 - Springer
Background This study aimed to investigate the association between the triglyceride–
glucose (TyG) index and left ventricular global longitudinal strain (GLS) in patients with …

Association between the liver fat score (LFS) and cardiovascular diseases in the national health and nutrition examination survey 1999–2016

CO Lee, HL Li, MF Tsoi, CL Cheung… - Annals of …, 2021 - Taylor & Francis
Background The liver fat score (LFS) has been proposed to be a simple non-invasive marker
of non-alcoholic fatty liver disease (NAFLD), which is highly prevalent in the general …

The association of insulin resistance measured through the estimated glucose disposal rate with predictors of micro-and macrovascular complications in patients with …

G Karamanakos, A Barmpagianni, CJ Kapelios… - Primary Care …, 2022 - Elsevier
Background and aim Insulin resistance (IR) is associated with a higher rate of type 1
diabetes (T1D) complications. We aimed to examine the relationship between estimated …

Association between the atherogenic index of plasma and left ventricular hypertrophy in patients with obstructive sleep apnea: a retrospective cross-sectional study

M Sun, C Liang, H Lin, Z Chen, M Wang, S Fang… - Lipids in Health and …, 2024 - Springer
Background The atherogenic index of plasma (AIP) is a simple and reliable marker of insulin
resistance and is closely associated with various cardiovascular diseases (CVDs). However …