Essential roles of intracellular calcium release channels in muscle, brain, metabolism, and aging
G Santulli, AR Marks - Current molecular pharmacology, 2015 - ingentaconnect.com
Calcium (Ca2+) release from intracellular stores controls numerous cellular processes,
including cardiac and skeletal muscle contraction, synaptic transmission and metabolism …
including cardiac and skeletal muscle contraction, synaptic transmission and metabolism …
The role of skeletal muscle in amyotrophic lateral sclerosis
JP Loeffler, G Picchiarelli, L Dupuis… - Brain …, 2016 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal adult‐onset disease primarily characterized by
upper and lower motor neuron degeneration, muscle wasting and paralysis. It is increasingly …
upper and lower motor neuron degeneration, muscle wasting and paralysis. It is increasingly …
Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis
MD Cykowski, SZ Powell, JW Appel… - Acta neuropathologica …, 2018 - Springer
Muscle atrophy with weakness is a core feature of amyotrophic lateral sclerosis (ALS) that
has long been attributed to motor neuron loss alone. However, several studies in ALS …
has long been attributed to motor neuron loss alone. However, several studies in ALS …
Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis
Sporadic inclusion body myositis (IBM) is the most common primary myopathy in the elderly,
but its pathoetiology is still unclear. Perturbed myocellular calcium (Ca 2+) homeostasis can …
but its pathoetiology is still unclear. Perturbed myocellular calcium (Ca 2+) homeostasis can …
Dysregulated mitochondrial Ca2+ and ROS signaling in skeletal muscle of ALS mouse model
Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized
by motor neuron loss and prominent skeletal muscle wasting. Despite more than one …
by motor neuron loss and prominent skeletal muscle wasting. Despite more than one …
Impaired autophagy and defective mitochondrial function: converging paths on the road to motor neuron degeneration
BM Edens, N Miller, YC Ma - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Selective motor neuron degeneration is a hallmark of amyotrophic lateral sclerosis (ALS).
Around 10% of all cases present as familial ALS (FALS), while sporadic ALS (SALS) …
Around 10% of all cases present as familial ALS (FALS), while sporadic ALS (SALS) …
Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A* SOD1 amyotrophic lateral sclerosis mice
Mutations in Cu/Zn superoxide dismutase (SOD1) are one of the genetic causes of
Amyotrophic Lateral Sclerosis (ALS). Although the primary symptom of ALS is muscle …
Amyotrophic Lateral Sclerosis (ALS). Although the primary symptom of ALS is muscle …
Time course changes in in vivo muscle mechanical function and Ca2+ regulation of force following experimentally induced gradual ovarian failure in mice
The abrupt cessation of ovarian hormone release is associated with declines in muscle
contractile function, yet the impact of gradual ovarian failure on muscle contractility across …
contractile function, yet the impact of gradual ovarian failure on muscle contractility across …
Conserved functions of RNA-binding proteins in muscle
E Nikonova, SY Kao, K Ravichandran, A Wittner… - … International Journal of …, 2019 - Elsevier
Animals require different types of muscle for survival, for example for circulation, motility,
reproduction and digestion. Much emphasis in the muscle field has been placed on …
reproduction and digestion. Much emphasis in the muscle field has been placed on …
[HTML][HTML] Potential Applications for Growth Hormone Secretagogues Treatment of Amyotrophic Lateral Sclerosis
R Meanti, E Bresciani, L Rizzi, S Coco… - Current …, 2023 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) arises from neuronal death due to complex interactions
of genetic, molecular, and environmental factors. Currently, only two drugs, riluzole and …
of genetic, molecular, and environmental factors. Currently, only two drugs, riluzole and …