[HTML][HTML] The secretion profile of mesenchymal stem cells and potential applications in treating human diseases
Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …
[HTML][HTML] The chemokines CXCL8 and CXCL12: molecular and functional properties, role in disease and efforts towards pharmacological intervention
S Cambier, M Gouwy, P Proost - Cellular & Molecular Immunology, 2023 - nature.com
Chemokines are an indispensable component of our immune system through the regulation
of directional migration and activation of leukocytes. CXCL8 is the most potent human …
of directional migration and activation of leukocytes. CXCL8 is the most potent human …
A guide to chemokines and their receptors
CE Hughes, RJB Nibbs - The FEBS journal, 2018 - Wiley Online Library
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms
Cancer-induced immune responses affect tumour progression and therapeutic response. In
multiple murine models and clinical datasets, we identified large variations of neutrophils …
multiple murine models and clinical datasets, we identified large variations of neutrophils …
[HTML][HTML] Potential roles and targeted therapy of the CXCLs/CXCR2 axis in cancer and inflammatory diseases
The chemokine receptor CXCR2 and its ligands are implicated in the progression of tumours
and various inflammatory diseases. Activation of the CXCLs/CXCR2 axis activates multiple …
and various inflammatory diseases. Activation of the CXCLs/CXCR2 axis activates multiple …
[HTML][HTML] A review of 3D polymeric scaffolds for bone tissue engineering: principles, fabrication techniques, immunomodulatory roles, and challenges
Over the last few years, biopolymers have attracted great interest in tissue engineering and
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …
TSG-6: A multifunctional protein with anti-inflammatory and tissue-protective properties
AJ Day, CM Milner - Matrix Biology, 2019 - Elsevier
Tumor necrosis factor-(TNF) stimulated gene-6 (TSG-6) is an inflammation-associated
secreted protein that has been implicated as having important and diverse tissue protective …
secreted protein that has been implicated as having important and diverse tissue protective …
[HTML][HTML] Recent advances to enhance the immunomodulatory potential of mesenchymal stem cells
Considering the unique therapeutic potential of mesenchymal stem cells (MSCs), including
their immunosuppressive and immunomodulatory properties as well as their ability to …
their immunosuppressive and immunomodulatory properties as well as their ability to …
[HTML][HTML] Chemokines from a structural perspective
MC Miller, KH Mayo - International journal of molecular sciences, 2017 - mdpi.com
Chemokines are a family of small, highly conserved cytokines that mediate various
biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that …
biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that …
[HTML][HTML] Hyaluronan, a crucial regulator of inflammation
AC Petrey, CA de la Motte - Frontiers in immunology, 2014 - frontiersin.org
Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in
regulating inflammation. Inflammation is associated with accumulation and turnover of HA …
regulating inflammation. Inflammation is associated with accumulation and turnover of HA …