Pancreatic ductal adenocarcinoma is a highly lethal malignancy, which has now become the
seventh most common cause of cancer death in the world, with the highest mortality rates in …

Simple Summary Although much progress has been made in recent years in the clinical
management of solid tumors, pancreatic ductal adenocarcinoma (PDAC) remains a …

Oral squamous cell carcinoma (OSCC) is a prevalent form of malignant tumor, characterized
by a persistently high incidence and mortality rate. The extracellular matrix (ECM) plays a …

Background As an integral part of the tumor microenvironment (TME), tumor-associated
neutrophils play a crucial role in tumor development. The objective of this study was to …

Aberrant sialylation plays a key biological role in tumorigenesis and metastasis, including
tumor cell survival and invasion, immune evasion, angiogenesis, and resistance to therapy …

Background The aim of this study was to construct a predictive signature integrating tumour-
mutation-and copy-number-variation-associated features using machine learning to …

Pancreatic ductal adenocarcinoma (PDAC) is known for its poor prognosis with few long-
term survivors. This study aimed to establish a prognostic score using unique transcriptomic …

Background Ovarian cancer (OC) has the highest mortality rate among gynecologic
malignancy. Hypoxia is a driver of the malignant progression in OC, which results in poor …

Background: Cellular senescence is a typical irreversible form of life stagnation, and recent
studies have suggested that long non-coding ribonucleic acids (lncRNA) regulate the …

Simple Summary Pancreatic cancer is one of the most lethal types of cancer, and
immunotherapy treatment options for these patients are limited by the characteristically …