Traditional approaches to solid rectal therapies have halted progress, leading to a continual
decline in the use of conventional suppositories. Additive manufacturing techniques have …

Background Small extracellular vesicles (sEVs) are emerging natural nanoplatforms in
cancer diagnosis and therapy, through the incorporation of signal components or drugs in …

Stem-cell-derived extracellular vesicles (EVs) have demonstrated multiple beneficial effects
in preclinical models of cardiac diseases. However, poor retention at the target site may limit …

Inflammation and oxidative stress (IOS) are considered key pathophysiological elements in
the development of mental disorders. Recent studies demonstrated that the antipsychotic …

Purpose The goal of this study was to compare the tumor uptake kinetics and diagnostic
value of three 68Ga-DOTA-labeled somatostatin analogues (68Ga-DOTATOC, 68Ga …

This study evaluates the long-term effects of a six and 14-week morphine withdrawal in rats
pretreated with a cannabinoid agonist (CP-55,940, CP) during periadolescence. Wistar rats …

Purpose Image quality of positron emission tomography (PET) tracers that emits high-energy
positrons, such as Ga-68, Rb-82, or I-124, is significantly affected by positron range (PR) …

Background Experience-dependent plastic changes in the brain underlying complex forms
of learning are generally initiated when organisms are awake, and this may limit the earliest …

The increasing popularity of massively parallel architectures based on accelerators have
opened up the possibility of significantly improving the performance of X-ray computed …

Purpose To investigate changes in glucose brain metabolism after deep brain stimulation
(DBS) in the lateral hypothalamic area (LHA) in a rat model of obesity. Procedures Ten …