The cardiac benefits of exercise have been recognized for centuries. Studies have
undisputedly shown that regular exercise is beneficial for the cardiovascular system in …

Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major
pathological event leading to morbidity and mortality in those with coronary artery disease …

Rationale: Exercise training confers sustainable protection against ischemia–reperfusion
injury in animal models and has been associated with improved survival following a heart …

Myocardial ischemia–reperfusion (IR) injury is a major contributor to the morbidity and
mortality associated with coronary artery disease. Muscular exercise is a countermeasure to …

Despite a high prevalence of sudden cardiac death throughout the world, the mechanisms
that lead to ventricular arrhythmias are not fully understood. Over the last 20 years, a …

The use of short-term (1–5 days) treadmill running is becoming increasingly common as a
model to study physiological adaptations following the exercise. Although the beneficial …

Importance Exercise reduces the risk of cardiovascular events, including through an
underrecognized, clinically useful form of acute cardioprotection accessible after a single …

Exercise promotes cardioprotection in both humans and animals not only by reducing risk
factors associated with cardiovascular disease but by reducing myocardial infarction and …

Diseases of the heart (eg myocardial ischaemia reperfusion injury) remain the major cause
of death in the industrialized world. Therefore, developing a pragmatic countermeasure to …

Purpose Three to five consecutive days of endurance exercise can protect the heart against
an ischemia-reperfusion (IR) insult. However, the mechanisms responsible for this exercise …