[HTML][HTML] Coronavirus RNA proofreading: molecular basis and therapeutic targeting

F Robson, KS Khan, TK Le, C Paris, S Demirbag… - Molecular cell, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) that is wreaking havoc on worldwide
public health and economies has heightened awareness about the lack of effective antiviral …

[HTML][HTML] Structural characterization of SARS-CoV-2: where we are, and where we need to be

G Mariano, RJ Farthing, SLM Lale-Farjat… - Frontiers in molecular …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread in
humans in almost every country, causing the disease COVID-19. Since the start of the …

[HTML][HTML] SARS-CoV-2 disrupts splicing, translation, and protein trafficking to suppress host defenses

AK Banerjee, MR Blanco, EA Bruce, DD Honson… - Cell, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently identified
coronavirus that causes the respiratory disease known as coronavirus disease 2019 (COVID …

Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein

JCC Hsu, M Laurent-Rolle, JB Pawlak… - Proceedings of the …, 2021 - National Acad Sciences
The ongoing COVID-19 pandemic has caused an unprecedented global health crisis.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of …

Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV

KG Lokugamage, A Hage, M de Vries… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT SARS-CoV-2, a novel coronavirus (CoV) that causes COVID-19, has recently
emerged causing an ongoing outbreak of viral pneumonia around the world. While distinct …

[HTML][HTML] Innate immune evasion by human respiratory RNA viruses

M Kikkert - Journal of innate immunity, 2020 - karger.com
The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

Stilbene-based natural compounds as promising drug candidates against COVID-19

HM Wahedi, S Ahmad, SW Abbasi - Journal of Biomolecular …, 2021 - Taylor & Francis
The pandemic coronavirus disease (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) presents a great threat to public health. Currently …

Host factors in coronavirus replication

AH De Wilde, EJ Snijder, M Kikkert… - Roles of host gene and …, 2018 - Springer
Coronaviruses are pathogens with a serious impact on human and animal health. They
mostly cause enteric or respiratory disease, which can be severe and life threatening, eg, in …

[PDF][PDF] SARS-CoV-2 is sensitive to type I interferon pretreatment

KG Lokugamage, A Hage, C Schindewolf, R Rajsbaum… - BioRxiv, 2020 - scienceopen.com
Abstract 1 SARS-CoV-2, a novel coronavirus (CoV), has recently emerged causing an
ongoing outbreak of 2 viral pneumonia around the world. While genetically distinct from the …

[HTML][HTML] Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug …

D Butler, C Mozsary, C Meydan, J Foox… - Nature …, 2021 - nature.com
In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) killed over a million people, including> 25,000 in New York City (NYC) alone. The …