[HTML][HTML] Oxidative stress and neuroinflammation in Parkinson's disease: the role of dopamine oxidation products
S Chakrabarti, M Bisaglia - Antioxidants, 2023 - mdpi.com
Parkinson's disease (PD) is a chronic neurodegenerative condition affecting more than 1%
of people over 65 years old. It is characterized by the preferential degeneration of …
of people over 65 years old. It is characterized by the preferential degeneration of …
[HTML][HTML] The potential for natural antioxidant supplementation in the early stages of neurodegenerative disorders
F Oppedisano, J Maiuolo, M Gliozzi… - International journal of …, 2020 - mdpi.com
The neurodegenerative process is characterized by the progressive ultrastructural
alterations of selected classes of neurons accompanied by imbalanced cellular …
alterations of selected classes of neurons accompanied by imbalanced cellular …
[HTML][HTML] N-Acetylcysteine Nanocarriers Protect against Oxidative Stress in a Cellular Model of Parkinson's Disease
Oxidative stress is a key mediator in the development and progression of Parkinson's
disease (PD). The antioxidant N-acetylcysteine (NAC) has generated interest as a disease …
disease (PD). The antioxidant N-acetylcysteine (NAC) has generated interest as a disease …
Interaction of α-synuclein and Parkin in iron toxicity on SH-SY5Y cells: implications in the pathogenesis of Parkinson's disease
The toxicity of accumulated α-synuclein plays a key role in the neurodegeneration of
Parkinson's disease (PD). This study has demonstrated that iron in varying concentrations …
Parkinson's disease (PD). This study has demonstrated that iron in varying concentrations …
[HTML][HTML] Protective effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells
T Zheng, DF Bielinski, DR Fisher, J Zhang… - Molecules, 2022 - mdpi.com
The aging process impacts neural stem cells and causes a significant decline in
neurogenesis that contributes to neuronal dysfunction leading to cognitive decline …
neurogenesis that contributes to neuronal dysfunction leading to cognitive decline …
[HTML][HTML] Oxidized alginate dopamine conjugate: in vitro characterization for nose-to-brain delivery application
Background: The blood–brain barrier (BBB) bypass of dopamine (DA) is still a challenge for
supplying it to the neurons of Substantia Nigra mainly affected by Parkinson disease. DA …
supplying it to the neurons of Substantia Nigra mainly affected by Parkinson disease. DA …
Protective effects of cyclosporine A on neurodegeneration and motor impairment in rotenone-induced experimental models of Parkinson's disease
The development of neuroprotective drugs targeting mitochondria could be an important
strategy in combating the progressive clinical course of Parkinson's disease. In the current …
strategy in combating the progressive clinical course of Parkinson's disease. In the current …
Apelin-36 exerts the cytoprotective effect against MPP+-induced cytotoxicity in SH-SY5Y cells through PI3K/Akt/mTOR autophagy pathway
J Zhu, S Dou, Y Jiang, B Bai, J Chen, C Wang… - Life sciences, 2019 - Elsevier
Aims Parkinson's disease (PD) is a common neurodegenerative disease typically
associated with the accumulation of α-synuclein. Autophagy impairment is thought to be …
associated with the accumulation of α-synuclein. Autophagy impairment is thought to be …
Is 1, 8-cineole-rich extract of small cardamom seeds more effective in preventing Alzheimer's disease than 1, 8-cineole alone?
The present study demonstrates the efficacies of synthetic 1, 8-cineole and an 1, 8-cineole-
rich supercritical carbon dioxide (SC-CO 2) extract of small cardamom seeds in preventing …
rich supercritical carbon dioxide (SC-CO 2) extract of small cardamom seeds in preventing …
[HTML][HTML] Three-dimensional directional nerve guide conduits fabricated by dopamine-functionalized conductive carbon nanofibre-based nanocomposite ink printing
A potential issue in current nerve guides is that they do not transmit electrical nerve impulses
between the distal and proximal end of an injured nerve, ie a synapse. Conductivity is a …
between the distal and proximal end of an injured nerve, ie a synapse. Conductivity is a …