Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

Phospholipase D is a ubiquitous class of enzymes that generates phosphatidic acid as an
intracellular signaling species. The phospholipase D superfamily plays a central role in a …

In mammals, white adipose tissues are largely divided into visceral epididymal adipose
tissue (EAT) and subcutaneous inguinal adipose tissue (IAT) with distinct metabolic …

One of the basic functions of insulin in the body is to inhibit lipolysis in adipocytes. Recently,
we have found that insulin inhibits lipolysis and promotes triglyceride storage by decreasing …

Adipocytes are the main cell type in adipose tissue, which is a critical regulator of
metabolism, highly specialized in storing energy as fat. Adipocytes differentiate from …

Adipogenesis is a process that differentiates new adipocytes from precursor cells and is
tightly regulated by several factors, including many transcription factors and various post …

Iberian ham production includes both purebred (IB) and Duroc-crossbred (IBxDU) Iberian
pigs, which show important differences in meat quality and production traits, such as muscle …

One of the most important determinants of meat quality is the intramuscular fat (IMF) content.
The development of high-throughput techniques as RNA-seq allows identifying gene …

c-Myc is frequently deregulated in human cancers. Although deregulated c-Myc leads to
tumor growth, it also triggers apoptosis in partnership with tumor suppressors such as ARF …

Proteins containing the zinc finger domain (s) are named zinc finger proteins (ZFPs), one of
the largest classes of transcription factors in eukaryotic genomes. A large number of ZFPs …