Generalized Born (GB) models provide an attractive way to include some thermodynamic
aspects of aqueous solvation into simulations that do not explicitly model the solvent …

DNA was selected over the course of evolution as the ideal molecule for coding and storing
the genetic blueprint of life. One primary driving force for selecting DNA as the repository for …

When talking about research, I must mention Mrs. Rita Wagner, a superb technician that
looked after my laboratory and the younger Ph. D. students for about 25 years. Some of her …

In the last five years we have witnessed a significant increase in the number publications
describing accurate and reliable all‐atom molecular dynamics simulations of nucleic acids …

Background The structure and dynamics of DNA are critically related to its function.
Molecular dynamics simulations augment experiment by providing detailed information …

We review molecular dynamics simulations of nucleic acids, including those completed from
1995 to 2000, with a focus on the applications and results rather than the methods. After the …

This volume is a timely and comprehensive description of the many facets of DNA and RNA
modification-editing processes and to some extent repair mechanisms. Each chapter offers …

When a single double-strand break arises in the genome, nonhomologous DNA end joining
(NHEJ) is a major pathway for its repair. When double-strand breaks arise at two …

Single-molecule force experiments provide powerful new tools to explore biomolecular
interactions. Here, we describe a systematic procedure for extracting kinetic information from …

The article reviews the application of biomolecular simulation methods to understand the
structure, dynamics and interactions of nucleic acids with a focus on explicit solvent …