Idiopathic pulmonary fibrosis (IPF) is a progressive and terminal lung disease with no known
cure. IPF is a disease of aging, with median age of diagnosis over 65 years. Median survival …

The recovery of an intact epithelium following lung injury is critical for restoration of lung
homeostasis. The initial processes following injury include an acute inflammatory response …

Developmental lung biology is a field that has the potential for significant human impact:
lung disease at the extremes of age continues to cause major morbidity and mortality …

All tissues and organs can be classified according to their ability to repair and regenerate
during adult homeostasis and after injury. Some exhibit a high rate of constant cell turnover …

Although there is accumulated evidence of a role for Notch in the developing lung, it is still
unclear how disruption of Notch signaling affects lung progenitor cell fate and differentiation …

There are a number of conditions of the bladder that can lead to loss of function. Many of
these require reconstructive procedures. However, current techniques may lead to a number …

The airways are conduits that transport atmospheric oxygen to the distal alveolus. Normally,
airway mucous cells are rare. However, diseases of the airway are often characterized by …

The WNT family of signaling proteins is essential to organ development in general and lung
morphogenesis in particular. Originally identified as a developmentally active signaling …

This study describes a novel type of interstitial (stromal) cell—telocytes (TCs)—in the human
and mouse respiratory tree (terminal and respiratory bronchioles, as well as alveolar ducts) …

Interstitial lung disease (ILD) in infants and children comprises a large spectrum of rare
respiratory disorders that are mostly chronic and associated with high morbidity and …