Mortality in people with schizophrenia: a systematic review and meta‐analysis of relative risk and aggravating or attenuating factors

CU Correll, M Solmi, G Croatto, LK Schneider… - World …, 2022 - Wiley Online Library
People with schizophrenia die 15‐20 years prematurely. Understanding mortality risk and
aggravating/attenuating factors is essential to reduce this gap. We conducted a systematic …

Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions

N Robinson, SE Bergen - Frontiers in genetics, 2021 - frontiersin.org
Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …

Premature mortality among adults with schizophrenia in the United States

M Olfson, T Gerhard, C Huang, S Crystal… - JAMA …, 2015 - jamanetwork.com
Importance Although adults with schizophrenia have a significantly increased risk of
premature mortality, sample size limitations of previous research have hindered the …

Association of a prior psychiatric diagnosis with mortality among hospitalized patients with coronavirus disease 2019 (COVID-19) infection

L Li, F Li, F Fortunati, JH Krystal - JAMA network open, 2020 - jamanetwork.com
Psychiatric disorders are associated with shortened life expectancy (ie, shortened by as
much as 10 years). 1 There is a concern that psychiatric comorbidity might increase …

Pathophysiological mechanisms of increased cardiometabolic risk in people with schizophrenia and other severe mental illnesses

DC Henderson, B Vincenzi, NV Andrea… - The Lancet …, 2015 - thelancet.com
Patients with schizophrenia have increased mortality and morbidity compared with the
general population. These patients have a 20-year shorter lifespan than peers without …

Understanding excess mortality in persons with mental illness: 17-year follow up of a nationally representative US survey

BG Druss, L Zhao, S Von Esenwein, EH Morrato… - Medical care, 2011 - journals.lww.com
Background Although growing concern has been expressed about premature medical
mortality in persons with mental illness, limited data are available quantifying the extent and …

Gaps in understanding health and engagement with healthcare providers across common long-term conditions: a population survey of health literacy in 29 473 …

K Friis, M Lasgaard, RH Osborne, HT Maindal - BMJ open, 2016 - bmjopen.bmj.com
Objectives To (1) quantify levels of subjective health literacy in people with long-term health
conditions (diabetes, cardiovascular disease, chronic obstructive pulmonary disease …

The STRIDE weight loss and lifestyle intervention for individuals taking antipsychotic medications: a randomized trial

CA Green, BJH Yarborough, MC Leo… - American Journal of …, 2015 - Am Psychiatric Assoc
Objectives: The STRIDE study assessed whether a lifestyle intervention, tailored for
individuals with serious mental illnesses, reduced weight and diabetes risk. The authors …

Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia

A Campeau, RH Mills, T Stevens, LA Rossitto… - Molecular …, 2022 - nature.com
Schizophrenia is a devastating psychiatric illness that detrimentally affects a significant
portion of the worldwide population. Aging of schizophrenia patients is associated with …

Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia

EG Severance, KL Gressitt, CR Stallings… - Schizophrenia …, 2013 - Elsevier
The origin of inflammation in psychiatric disorders is not well understood. The translocation
of commensal microbiota across the gastrointestinal barrier can result in a persistent state of …