Community detection and stochastic block models: recent developments
E Abbe - Journal of Machine Learning Research, 2018 - jmlr.org
The stochastic block model (SBM) is a random graph model with planted clusters. It is widely
employed as a canonical model to study clustering and community detection, and provides …
employed as a canonical model to study clustering and community detection, and provides …
Rationally engineered nucleic acid architectures for biosensing applications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
Protein‐protein interaction detection: methods and analysis
VS Rao, K Srinivas, GN Sujini… - International journal of …, 2014 - Wiley Online Library
Protein‐protein interaction plays key role in predicting the protein function of target protein
and drug ability of molecules. The majority of genes and proteins realize resulting …
and drug ability of molecules. The majority of genes and proteins realize resulting …
AF2Complex predicts direct physical interactions in multimeric proteins with deep learning
Accurate descriptions of protein-protein interactions are essential for understanding
biological systems. Remarkably accurate atomic structures have been recently computed for …
biological systems. Remarkably accurate atomic structures have been recently computed for …
[HTML][HTML] MINDY-1 is a member of an evolutionarily conserved and structurally distinct new family of deubiquitinating enzymes
SAA Rehman, YA Kristariyanto, SY Choi, PJ Nkosi… - Molecular cell, 2016 - cell.com
Deubiquitinating enzymes (DUBs) remove ubiquitin (Ub) from Ub-conjugated substrates to
regulate the functional outcome of ubiquitylation. Here we report the discovery of a new …
regulate the functional outcome of ubiquitylation. Here we report the discovery of a new …
[HTML][HTML] A large-scale evaluation of computational protein function prediction
Automated annotation of protein function is challenging. As the number of sequenced
genomes rapidly grows, the overwhelming majority of protein products can only be …
genomes rapidly grows, the overwhelming majority of protein products can only be …
Community detection in general stochastic block models: Fundamental limits and efficient algorithms for recovery
E Abbe, C Sandon - 2015 IEEE 56th Annual Symposium on …, 2015 - ieeexplore.ieee.org
New phase transition phenomena have recently been discovered for the stochastic block
model, for the special case of two non-overlapping symmetric communities. This gives raise …
model, for the special case of two non-overlapping symmetric communities. This gives raise …
The role of protein loops and linkers in conformational dynamics and allostery
Proteins are dynamic entities that undergo a plethora of conformational changes that may
take place on a wide range of time scales. These changes can be as small as the rotation of …
take place on a wide range of time scales. These changes can be as small as the rotation of …
Learning spatial structures of proteins improves protein–protein interaction prediction
Spatial structures of proteins are closely related to protein functions. Integrating protein
structures improves the performance of protein–protein interaction (PPI) prediction …
structures improves the performance of protein–protein interaction (PPI) prediction …
Structure, dynamics, assembly, and evolution of protein complexes
JA Marsh, SA Teichmann - Annual review of biochemistry, 2015 - annualreviews.org
The assembly of individual proteins into functional complexes is fundamental to nearly all
biological processes. In recent decades, many thousands of homomeric and heteromeric …
biological processes. In recent decades, many thousands of homomeric and heteromeric …