Transition metals-catalyzed amination of biomass feedstocks for sustainable construction of N-heterocycles

Q Yan, X Wu, H Jiang, H Wang, F Xu, H Li… - Coordination Chemistry …, 2024 - Elsevier
Transition metals, which are of diversity in their bonding orbitals, have a variety of significant
oxidation states and more complex chemical properties compared to the main group metals …

Bioactive 2-pyridone-containing heterocycle syntheses using multicomponent reactions

D Hurtado-Rodríguez, A Salinas-Torres, H Rojas… - RSC …, 2022 - pubs.rsc.org
2-Pyridone-containing heterocycles are considered privileged scaffolds in drug discovery
due to their behavior as hydrogen bond donors and/or acceptors and nonpeptidic mimics …

Catalytic application Fe3O4@ SiO2@(CH2) 3-urea-dithiocarbamic acid for the synthesis of triazole-linked pyridone derivatives

MR Anizadeh, M Torabi, MA Zolfigol, M Yarie - Journal of Molecular …, 2023 - Elsevier
In this study, synthesis and characterization of an acidic-hydrogen bonding dual role and
recoverable catalyst [Fe 3 O 4@ SiO 2@(CH 2) 3-urea-dithiocarbamic acid] was reported …

Design, synthesis, and anti-bacterial activities of piperazine based phthalimide derivatives against superbug-Methicillin-Resistant Staphylococcus aureus

H Prasad, A Ananda, A Mukarambi… - Current Chemistry …, 2023 - growingscience.com
A series of piperazine-based phthalimide derivatives 5 (al) were synthesized and
extensively characterized using a variety of spectrum methods, including LC-MS, 1H-NMR …

Theoretical investigation of tautomerism of 2-and 4-pyridones: origin, substituent and solvent effects

M Baranac-Stojanović, J Aleksić… - Organic & Biomolecular …, 2024 - pubs.rsc.org
Computational investigation at the BHandHLYP/6-311+ G (d, p) level of theory of the gas-
phase tautomerism of 2-and 4-pyridones confirmed the slight prevalence of lactim in the …

Two New 4-Hydroxy-2-pyridone Alkaloids with Antimicrobial and Cytotoxic Activities from Arthrinium sp. GZWMJZ-606 Endophytic with Houttuynia cordata Thunb

Y Yin, D Wang, D Wu, W He, M Zuo, W Zhu, Y Xu… - Molecules, 2023 - mdpi.com
Two new 4-hydroxy-2-pyridone alkaloids furanpydone A and B (1 and 2), along with two
known compounds N-hydroxyapiosporamide (3) and apiosporamide (4) were isolated from …

The “cesium effect” magnified: exceptional chemoselectivity in cesium ion mediated nucleophilic reactions

S Biswas, WB Hughes, L De Angelis, GC Haug… - Chemical …, 2024 - pubs.rsc.org
Chemodivergent construction of structurally distinct heterocycles from the same precursors
by adjusting specific reaction parameters is an emergent area of organic synthesis; yet …

[HTML][HTML] In-silico evaluation of bioactive compounds from selected medicinal plants from Southern Nigeria against hepatitis C virus genotype 1 RNA-directed RNA …

CI Mboto, UO Edet, EN Mbim, WO Ndifon, EE Ebenso… - Scientific African, 2023 - Elsevier
Background At the moment, there is no vaccine for the hepatitis C virus (HCV), despite it
being more infectious than the hepatitis B virus (HBV) and the human immunodeficiency …

Modular Approach to Highly Substituted 3-Methylpyridones

Y Zhang, H Chen, L Zheng, L Shi, X Che… - The Journal of …, 2024 - ACS Publications
A method has been developed for the rapid synthesis of highly substituted 3-
methylpyridones via the condensation of Baylis–Hillman amines and ketones under benzoic …

[HTML][HTML] Towards designing of some potential new autoimmune disorder inhibitors using crystal structures and Hirshfeld surface analyses in combination with …

EI Edache, A Uzairu, PA Mamza, GA Shallangwa… - Intelligent …, 2024 - Elsevier
The emergence of multi-drug-resistant autoimmune diseases poses a significant risk to
human health and has garnered global attention. In this study, metformin and sulfasalazine …