The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

Callous-unemotional traits and the treatment of conduct problems in childhood and adolescence: A comprehensive review

DJ Hawes, MJ Price, MR Dadds - Clinical child and family psychology …, 2014 - Springer
The treatment of conduct problems among children and adolescents with callous-
unemotional (CU) traits has been subject to much speculation; however, treatment outcome …

Oxytocin and the neurobiology of prosocial behavior

N Marsh, AA Marsh, MR Lee… - The …, 2021 - journals.sagepub.com
Humans are an unusually prosocial species, who engage in social behaviors that include
altruism—whereby an individual engages in costly or risky acts to improve the welfare of …

The role of epigenetic change in autism spectrum disorders

YJ Loke, AJ Hannan, JM Craig - Frontiers in neurology, 2015 - frontiersin.org
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …

Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain

MH Puglia, TS Lillard, JP Morris… - Proceedings of the …, 2015 - National Acad Sciences
In humans, the neuropeptide oxytocin plays a critical role in social and emotional behavior.
The actions of this molecule are dependent on a protein that acts as its receptor, which is …

[图书][B] Evolutionary psychopathology: A unified approach

M Del Giudice - 2018 - books.google.com
Mental disorders arise from neural and psychological mechanisms that have been built and
shaped by natural selection across our evolutionary history. Looking at psychopathology …

The caring continuum: Evolved hormonal and proximal mechanisms explain prosocial and antisocial extremes

AA Marsh - Annual Review of Psychology, 2019 - annualreviews.org
Implicit in the long-standing disagreements about whether humans' fundamental nature is
predominantly caring or callous is an assumption of uniformity. This article reviews evidence …

Childhood maternal care is associated with DNA methylation of the genes for brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) in peripheral …

E Unternaehrer, AH Meyer, SCA Burkhardt… - Stress, 2015 - Taylor & Francis
In adults, reporting low and high maternal care in childhood, we compared DNA methylation
in two stress-associated genes (two target sequences in the oxytocin receptor gene, OXTR; …

Oxytocin receptor genetic and epigenetic variations: association with child abuse and adult psychiatric symptoms

EL Smearman, LM Almli, KN Conneely… - Child …, 2016 - Wiley Online Library
Childhood abuse can alter biological systems and increase risk for adult psychopathology.
Epigenetic mechanisms, alterations in DNA structure that regulate the gene expression, are …