The general transcription machinery and general cofactors
MC Thomas, CM Chiang - Critical reviews in biochemistry and …, 2006 - Taylor & Francis
In eukaryotes, the core promoter serves as a platform for the assembly of transcription
preinitiation complex (PIC) that includes TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA …
preinitiation complex (PIC) that includes TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA …
The Ubiquitin–Proteasome System of Saccharomyces cerevisiae
Protein modifications provide cells with exquisite temporal and spatial control of protein
function. Ubiquitin is among the most important modifiers, serving both to target hundreds of …
function. Ubiquitin is among the most important modifiers, serving both to target hundreds of …
Histone ubiquitination: triggering gene activity
VM Weake, JL Workman - Molecular cell, 2008 - cell.com
Recently, many of the enzymes responsible for the addition and removal of ubiquitin from
the histones H2A and H2B have been identified and characterized. From these studies, it …
the histones H2A and H2B have been identified and characterized. From these studies, it …
Ubiquitin and proteasomes in transcription
F Geng, S Wenzel, WP Tansey - Annual review of biochemistry, 2012 - annualreviews.org
Regulation of gene transcription is vitally important for the maintenance of normal cellular
homeostasis. Failure to correctly regulate gene expression, or to deal with problems that …
homeostasis. Failure to correctly regulate gene expression, or to deal with problems that …
The Ccr4–not complex
MA Collart, OO Panasenko - Gene, 2012 - Elsevier
The Ccr4–Not complex is a unique, essential and conserved multi-subunit complex that acts
at the level of many different cellular functions to regulate gene expression. Two enzymatic …
at the level of many different cellular functions to regulate gene expression. Two enzymatic …
[HTML][HTML] Regulatory functions of nuclear hexokinase1 complex in glucose signaling
YH Cho, SD Yoo, J Sheen - Cell, 2006 - cell.com
Summary Arabidopsis hexokinase1 (HXK1) is a glucose sensor that integrates nutrient and
hormone signals to govern gene expression and plant growth in response to environmental …
hormone signals to govern gene expression and plant growth in response to environmental …
20S proteasome and its inhibitors: crystallographic knowledge for drug development
L Borissenko, M Groll - Chemical reviews, 2007 - ACS Publications
Principles of intracellular protein synthesis and protein degradation remain to be among the
most challenging questions of modern cell biology. Proteolysis plays an important role in …
most challenging questions of modern cell biology. Proteolysis plays an important role in …
Epstein–Barr virus and virus human protein interaction maps
MA Calderwood, K Venkatesan… - Proceedings of the …, 2007 - National Acad Sciences
A comprehensive mapping of interactions among Epstein–Barr virus (EBV) proteins and
interactions of EBV proteins with human proteins should provide specific hypotheses and a …
interactions of EBV proteins with human proteins should provide specific hypotheses and a …
Dynamic regulation of PGC‐1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response
There is increasing evidence that longevity and stress resistance are connected, but the
mechanism is unclear. We report that mitochondria are regulated in response to oxidative …
mechanism is unclear. We report that mitochondria are regulated in response to oxidative …
Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells
J Ulvila, M Parikka, A Kleino, R Sormunen… - Journal of Biological …, 2006 - ASBMB
Double-stranded RNA (dsRNA) fragments are readily internalized and processed by
Drosophila S2 cells, making these cells a widely used tool for the analysis of gene function …
Drosophila S2 cells, making these cells a widely used tool for the analysis of gene function …