Stearoyl-CoA desaturase: rogue or innocent bystander?

L Hodson, BA Fielding - Progress in lipid research, 2013 - Elsevier
Different lipid fractions in humans have characteristic fatty acid profiles and these are
maintained partly through diet and to a lesser extent through endogenous synthesis. The …

Genome-Wide Association Study Singles Out SCD and LEPR as the Two Main Loci Influencing Intramuscular Fat Content and Fatty Acid Composition in Duroc Pigs

R Ros-Freixedes, S Gol, RN Pena, M Tor… - PLoS …, 2016 - journals.plos.org
Intramuscular fat (IMF) content and fatty acid composition affect the organoleptic quality and
nutritional value of pork. A genome-wide association study was performed on 138 Duroc …

SCD1 alters long‐chain fatty acid (LCFA) composition and its expression is directly regulated by SREBP‐1 and PPARγ 1 in dairy goat mammary cells

D Yao, J Luo, Q He, H Shi, J Li, H Wang… - Journal of cellular …, 2017 - Wiley Online Library
Stearoyl‐CoA desaturase 1 (SCD1) is a key enzyme for the synthesis of the
monounsaturated fatty acids (MUFA) palmitoleic acid and oleic acid. In non‐ruminant …

A functional variant in the stearoyl-CoA desaturase gene promoter enhances fatty acid desaturation in pork

J Estany, R Ros-Freixedes, M Tor, RN Pena - PLoS One, 2014 - journals.plos.org
There is growing public concern about reducing saturated fat intake. Stearoyl-CoA
desaturase (SCD) is the lipogenic enzyme responsible for the biosynthesis of oleic acid …

Differences in Muscle Lipogenic Gene Expression, Carcass Traits and Fat Deposition among Three Iberian Pig Strains Finished in Two Different Feeding Systems

N Garrido, M Izquierdo, FI Hernández-García, Y Núñez… - Animals, 2023 - mdpi.com
Simple Summary The Iberian pig is known for the high quality of its products, mostly due to
the unique lipid profile of its meat. There are several studies comparing commercial breeds …

Effects of omega-3 and-6 polyunsaturated fatty acids on ovine follicular cell steroidogenesis, embryo development and molecular markers of fatty acid metabolism

J Hughes, WY Kwong, D Li, AM Salter, RG Lea… - …, 2011 - rep.bioscientifica.com
We previously reported increased follicular fluid progesterone (P4) concentrations in ewes
fed an n-3 compared to an n-6 polyunsaturated fatty acid (PUFA)-enriched diet, but detected …

Dynamic transcriptome and DNA methylome analyses on longissimus dorsi to identify genes underlying intramuscular fat content in pigs

Y Wang, C Ma, Y Sun, Y Li, L Kang, Y Jiang - BMC genomics, 2017 - Springer
Background The intramuscular fat content (IMF) refers to the amount of fat within muscles,
including the sum of phospholipids mainly found in cell membranes, triglycerides and …

Fatty acid biosynthesis and lipogenic enzyme activities in subcutaneous adipose tissue of feedlot steers fed supplementary palm oil or soybean oil

SH Choi, GO Gang, JE Sawyer… - Journal of Animal …, 2013 - academic.oup.com
We hypothesized that supplementing finishing diets with palm oil would promote adipocyte
differentiation in subcutaneous adipose tissue of feedlot steers, and that soybean oil …

Allele-specific effect of various dietary fatty acids and ETS1 transcription factor on SCD1 expression

K Tibori, V Zámbó, G Orosz, P Szelényi, F Sarnyai… - Scientific Reports, 2024 - nature.com
Overnutrition and genetic predisposition are major risk factors for various metabolic
disorders. Stearoyl-CoA desaturase-1 (SCD1) plays a key role in these conditions by …

Effects of dietary fat saturation on fatty acid composition and gene transcription in different tissues of Iberian pigs

R Benítez, Y Núñez, A Fernández, B Isabel… - Meat science, 2015 - Elsevier
The effect of two diets, respectively enriched with SFA (S) and PUFA (P), on FA tissue
composition and gene expression was studied in fattened Iberian pigs. The FA composition …