Canonical and noncanonical TGF-β signaling regulate fibrous tissue differentiation in the axial skeleton
Previously, we showed that embryonic deletion of TGF-β type 2 receptor in mouse
sclerotome resulted in defects in fibrous connective tissues in the spine. Here we …
sclerotome resulted in defects in fibrous connective tissues in the spine. Here we …
Building a vertebra: Development of the amniote sclerotome
M Draga, M Scaal - Journal of Morphology, 2024 - Wiley Online Library
In embryonic development, the vertebral column arises from the sclerotomal compartment of
the somites. The sclerotome is a mesenchymal cell mass which can be subdivided into …
the somites. The sclerotome is a mesenchymal cell mass which can be subdivided into …
[HTML][HTML] Inactivation of FAM20B causes cell fate changes in annulus fibrosus of mouse intervertebral disc and disc defects via the alterations of TGF-β and MAPK …
Intervertebral disc (IVD) disorder is often caused by the defect of annulus fibrosus (AF),
especially that of the outer AF. Studies about the mechanisms governing the development of …
especially that of the outer AF. Studies about the mechanisms governing the development of …
Intervertebral Disc Progenitors: Lessons Learned from Single-Cell RNA Sequencing and the Role in Intervertebral Disc Regeneration
YD Zhao, YC Huang, JL Lin, WS Li - Bioengineering, 2023 - mdpi.com
The tremendous personal and economic burden worldwide caused by low back pain (LBP)
has been surging in recent years. While intervertebral disc degeneration (IVDD) is the …
has been surging in recent years. While intervertebral disc degeneration (IVDD) is the …
Sp1 promotes dental pulp stem cell osteoblastic differentiation through regulating noggin
C Xia, T Pan, N Zhang, J Guo, B Yang, D Zhang… - Molecular and cellular …, 2020 - Elsevier
Based on the high self-renewal ability and osteoblastic differentiation capacity, dental pulp
stem cells (DPSCs) are suggested to be promising cell source for osteogenesis. Therefore …
stem cells (DPSCs) are suggested to be promising cell source for osteogenesis. Therefore …
[HTML][HTML] TGFβ signaling is required for sclerotome resegmentation during development of the spinal column in Gallus gallus
SW Clayton, A Angermeier, JE Halbrooks… - Developmental …, 2022 - Elsevier
We previously showed the importance of TGFβ signaling in development of the mouse axial
skeleton. Here, we provide the first direct evidence that TGFβ signaling is required for …
skeleton. Here, we provide the first direct evidence that TGFβ signaling is required for …
Investigating the Structure and Function of ADAMTSL2
M Singh - 2022 - search.proquest.com
Abstract ADAMTSL (A Disintegrin and Metalloprotease with Thrombospondin type 1 motifs-
like) proteins have important roles in the extracellular matrix (ECM), highlighted by their link …
like) proteins have important roles in the extracellular matrix (ECM), highlighted by their link …