Mitochondrial outer membrane permeabilization (MOMP) constitutes one of the major
checkpoint (s) of apoptotic and necrotic cell death. Recently, the permeabilization of yet …

Lysosomal membrane permeabilization (LMP) occurs in response to a large variety of cell
death stimuli causing release of cathepsins from the lysosomal lumen into the cytosol where …

Curcumin, a major active component of turmeric (Curcuma longa, L.), has anticancer effects.
In vitro studies suggest that curcumin inhibits cancer cell growth by activating apoptosis, but …

Cells undergo apoptosis through two major pathways, the extrinsic pathway (death receptor
pathway) and the intrinsic pathway (the mitochondrial pathway). It is well known that …

Macrobrachium nipponense is an economically and nutritionally important species
threatened by ambient superfluous nitrite. De novo RNA-Seq was used to explore the …

Chymotrypsin is a medication that is useful in treating inflammation, edema, expectoration,
and corruption. It has a wide range of medical applications. Therefore, it is critical to create a …

Chymotrypsin, an extensively known proteolytic enzyme, plays a substantial role in
maintaining physiological functions, including protein digestion, immune response, and …

We developed 1-[4-(N-benzylamino) phenyl]-3-phenylurea derivative 4 (GN6958) as a non-
peptidic selective SUMO-sentrin specific protease (SENP) 1 protease inhibitor based on the …

Upon apoptotic stimuli, lysosomal proteases, including cathepsins and chymotrypsin, are
released into cytosol due to lysosomal membrane permeabilization (LMP), where they …

Abstract L929 fibroblastoma cells (L929-A) and L929 fibrosarcoma cells (L929-N) are
different cell lines that are commonly used to study the cytotoxicity of tumor necrosis factor …