Tetraspanins: host factors in viral infections

CS New, ZY Lee, KS Tan, AHP Wong… - International Journal of …, 2021 - mdpi.com
Tetraspanins are transmembrane glycoproteins that have been shown increasing interest as
host factors in infectious diseases. In particular, they were implicated in the pathogenesis of …

Imaging of surface microdomains on individual extracellular vesicles in 3‐D

RP McNamara, Y Zhou, AB Eason… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are secreted from all cell types and are intimately involved in
tissue homeostasis. They are being explored as vaccine and gene therapy platforms, as well …

Exosomal transmission of viruses, a two-edged biological sword

N Mardi, S Haiaty, R Rahbarghazi, H Mobarak… - Cell Communication and …, 2023 - Springer
As a common belief, most viruses can egress from the host cells as single particles and
transmit to uninfected cells. Emerging data have revealed en bloc viral transmission as lipid …

Extracellular vesicles are conveyors of the NS1 toxin during dengue virus and Zika virus infection

DE Safadi, G Lebeau, A Lagrave, J Mélade, L Grondin… - Viruses, 2023 - mdpi.com
Extracellular vesicles (EVs), produced during viral infections, are of emerging interest in
understanding infectious processes and host–pathogen interactions. EVs and exosomes in …

Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells

PK Jadi, A Dave, R Issa, K Tabbasum, K Okurowska… - The Ocular Surface, 2024 - Elsevier
Pseudomonas aeruginosa is a leading cause of corneal infection both within India and
globally, often causing a loss of vision. Increasing antimicrobial resistance among the …

The anti-immune dengue subgenomic flaviviral RNA is present in vesicles in mosquito saliva and is associated with increased infectivity

SC Yeh, T Strilets, WL Tan, D Castillo… - PLoS …, 2023 - journals.plos.org
Mosquito transmission of dengue viruses to humans starts with infection of skin resident
cells at the biting site. There is great interest in identifying transmission-enhancing factors in …

Characterization and involvement of exosomes originating from Chikungunya virus-infected epithelial cells in the transmission of infectious viral elements

BCT Le, A Burassakarn, P Tongchai… - International journal of …, 2022 - mdpi.com
The Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that affects the world's
popula-tion with chikungunya disease. Adaptation of the viral life cycle to their host cells' …

Zika virus-infected monocyte exosomes mediate cell-to-cell viral transmission

PP Martínez-Rojas, V Monroy-Martínez… - Cells, 2024 - mdpi.com
Zika fever is a reemerging arthropod-borne viral disease; however, Zika virus (ZIKV) can be
transmitted by other, non-vector means. Severe Zika fever is characterized by neurological …

Extracellular Vesicles in Flaviviridae Pathogenesis: Their Roles in Viral Transmission, Immune Evasion, and Inflammation

A Latanova, V Karpov, E Starodubova - International Journal of Molecular …, 2024 - mdpi.com
The members of the Flaviviridae family are becoming an emerging threat for public health,
causing an increasing number of infections each year and requiring effective treatment. The …

Coordination of Zika virus infection and viroplasm organization by microtubules and microtubule-organizing centers

RA Buchwalter, SC Ogden, SB York, L Sun, C Zheng… - Cells, 2021 - mdpi.com
Zika virus (ZIKV) became a global health concern in 2016 due to its links to congenital
microcephaly and other birth defects. Flaviviruses, including ZIKV, reorganize the …