Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …

Microbial anaerobes are exposed in the natural environment and in their hosts, even if
transiently, to fluctuating concentrations of oxygen and its derived reactive species, which …

By eliminating unnecessary degrees of freedom, coarse-grained (CG) models tremendously
facilitate numerical calculations and theoretical analyses of complex phenomena. However …

Acquisition of transition metals is central to the struggle between a bacterial pathogen and
its mammalian host. Previous studies demonstrated that Treponema pallidum encodes a …

Superoxide anion is among the deleterious reactive oxygen species, towards which all
organisms have specialized detoxifying enzymes. For quite a long time, superoxide …

Cysteine dioxygenase (CDO) is a mononuclear non-heme Fe-dependent dioxygenase that
catalyzes the initial step of oxidative cysteine catabolism. Its active site consists of an Fe (II) …

A new five-coordinate,(N4S (thiolate)) FeII complex, containing tertiary amine donors,[FeII
(Me4 [15] aneN4)(SPh)] BPh4 (2), was synthesized and structurally characterized as a …

The microaerophilic protist Giardia intestinalis is the causative agent of giardiasis, one of the
most common intestinal infectious diseases worldwide. The pathogen lacks not only …

The Tp34 (TP0971) membrane lipoprotein of Treponema pallidum, an obligate human
pathogen and the agent of syphilis, was previously reported to have lactoferrin binding …

The non-heme iron complexes,[FeII (N3PySR)(CH3CN)](BF4) 2 (1) and [FeII
(N3PyamideSR)](BF4) 2 (2), afford rare examples of metastable Fe (III)-OOH and Fe (III) …