The fibroblast growth factor (FGF) family, which comprises 22 structurally related proteins,
plays diverse roles in cell proliferation, differentiation, development, and metabolism. Among …

Adipose tissue signals to brain, liver, and muscles to control whole body metabolism through
secreted lipid and protein factors as well as neurotransmission, but the mechanisms …

Exercise can prevent osteoporosis and improve immune function, but the mechanism
remains unclear. Here, we show that exercise promotes reticulocalbin-2 secretion from the …

Nonalcoholic fatty liver disease (NAFLD), a chronic condition associated with metabolic
dysfunction and obesity, has reached epidemic proportions worldwide. Although early …

Defects in adipocyte lipolysis drive multiple aspects of cardiometabolic disease, but the
transcriptional framework controlling this process has not been established. To address this …

Chronic non-healing wounds, a prevalent complication of diabetes, are associated with
increased mortality in diabetic patients. Excessive accumulation of M1 macrophages in …

The number of people with diabetes worldwide is increasing annually, resulting in a serious
economic burden. Insulin resistance is a major pathology in the early onset of diabetes …

Metabolites derived from the intestinal microbiota play an important role in maintaining
skeletal muscle growth, function, and metabolism. Here, we found that d-malate (DMA) is …

FGF/FGFR signaling is critical for the development and homeostasis of the human body and
imbalanced FGF/FGFR contributes to the progression of severe diseases, including cancers …

Metabolites | Free Full-Text | The Lipid Energy Model: Reimagining Lipoprotein Function in
the Context of Carbohydrate-Restricted Diets Next Article in Journal The Legend of ATP …