The mechanism of bacterial resistance and potential bacteriostatic strategies
F Zhang, W Cheng - Antibiotics, 2022 - mdpi.com
Bacterial drug resistance is rapidly developing as one of the greatest threats to human
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …
Advancements in bacteriophage therapies and delivery for bacterial infection
HA Durr, ND Leipzig - Materials Advances, 2023 - pubs.rsc.org
Having co-evolved with bacteria over hundreds of millions of years, bacteriophage are
effective killers of specific bacterial hosts. Therefore, phage therapies for infection are a …
effective killers of specific bacterial hosts. Therefore, phage therapies for infection are a …
Pulmonary delivery of emerging antibacterials for bacterial lung infections treatment
J Li, H Zheng, SSY Leung - Pharmaceutical research, 2023 - Springer
Bacterial infections in the respiratory tract are considered as one of the major challenges to
the public health worldwide. Pulmonary delivery is an attractive approach in the …
the public health worldwide. Pulmonary delivery is an attractive approach in the …
Mycobacteriophage–antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus
MD Johansen, M Alcaraz, RM Dedrick… - Disease models & …, 2021 - journals.biologists.com
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic
fibrosis (CF) patients, leaving clinicians with few therapeutic options. A compassionate study …
fibrosis (CF) patients, leaving clinicians with few therapeutic options. A compassionate study …
[HTML][HTML] Recent advancements in nanotechnology-based bacteriophage delivery strategies against bacterial ocular infections
Antibiotic resistance is growing as a critical challenge in a variety of disease conditions
including ocular infections leading to disastrous effects on the human eyes. Staphylococcus …
including ocular infections leading to disastrous effects on the human eyes. Staphylococcus …
Endolysins against Streptococci as an antibiotic alternative
KY Wong, MH Megat Mazhar Khair, AAL Song… - Frontiers in …, 2022 - frontiersin.org
Multi-drug resistance has called for a race to uncover alternatives to existing antibiotics.
Phage therapy is one of the explored alternatives, including the use of endolysins, which are …
Phage therapy is one of the explored alternatives, including the use of endolysins, which are …
First Characterization of a Hafnia Phage Reveals Extraordinarily Large Burst Size and Unusual Plaque Polymorphism
L Pan, D Li, Z Sun, W Lin, B Hong, W Qin, L Xu… - Frontiers in …, 2022 - frontiersin.org
A unique lytic phage infecting Hafnia paralvei was isolated and identified. Hafnia phage Ca
belongs to the family Autographiviridae, possessing an icosahedral head with a diameter of …
belongs to the family Autographiviridae, possessing an icosahedral head with a diameter of …
[HTML][HTML] Beyond antibiotics: what the future holds
P Benyamini - Antibiotics, 2024 - mdpi.com
The prevalence of multidrug resistance (MDR) and stagnant drug-development pipelines
have led to the rapid rise of hard-to-treat antibiotic-resistant bacterial infections. These …
have led to the rapid rise of hard-to-treat antibiotic-resistant bacterial infections. These …
The power of phages: revolutionizing cancer treatment
MS Islam, J Fan, F Pan - Frontiers in Oncology, 2023 - frontiersin.org
Cancer is a devastating disease with a high global mortality rate and is projected to increase
further in the coming years. Current treatment options, such as chemotherapy and radiation …
further in the coming years. Current treatment options, such as chemotherapy and radiation …
[HTML][HTML] Phages and phage-borne enzymes as new antibacterial agents
Background Persistent and resistant infections caused by bacteria are increasing in
numbers and pose a treatment challenge to the medical community and public health …
numbers and pose a treatment challenge to the medical community and public health …