Successful cell division requires the precise and timely coordination of chromosomal,
cytoskeletal and membrane trafficking events. These processes are regulated by the …

Condensins are multisubunit protein complexes that play a fundamental role in the structural
and functional organization of chromosomes in the three domains of life. Most eukaryotic …

Our understanding of the structure and function of mitotic chromosomes has come a long
way since these iconic objects were first recognized more than 140 years ago, though many …

Enduring chromosome segregation errors represent potential threats to genomic stability
due to eventual chromosome copy number alterations (aneuploidy) and formation of …

The regulation of carbon metabolism in the diatom Phaeodactylum tricornutum at the cell,
metabolite, and gene expression levels in exponential fed-batch cultures is reported …

Understanding the molecular network of orderly mitotic exit to re-establish a functional
interphase nucleus is critical because disordered mitotic exit inevitably leads to genomic …

The Chromosomal Passenger Complex (CPC) consisting of Aurora B kinase, INCENP,
Survivin and Borealin, is essential for genomic stability by controlling multiple processes …

Chromosome condensation is a hallmark of mitosis in eukaryotes and is a prerequisite for
faithful segregation of genetic material to daughter cells. Here we show that condensin …

Accurate chromosome segregation during mitosis requires the physical separation of sister
chromatids before nuclear envelope reassembly (NER). However, how these two processes …

The Aurora kinase family of kinases (Aurora A, B, and C) are involved in multiple mitotic
events, and aberrant expression of these kinases is associated with tumorigenesis. Aurora A …