Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …

Tumor Associated Neutrophils (TANs) are engaged into the tumor microenvironment by
cytokines and chemokines, can be distinguished according to their activation and cytokine …

Neutrophils are the most abundant leukocytes in blood and are considered to be the first line
of defense during inflammation and infections. In addition, neutrophils are also found …

Neutrophil elastase (NE), a major protease in the primary granules of neutrophils, is
involved in microbicidal activity. NE is an important factor promoting inflammation, has …

Tumors consist of cancer cells and a network of non-cancerous stroma. Cancer-associated
fibroblasts (CAF) are known to support tumorigenesis, and are emerging as immune …

Conversion therapy for gastric cancer (GC) has been the subject of much recent attention. It
is defined as a surgical treatment aiming at an R0 resection after chemotherapy for tumors …

In recent years, the role of neutrophils in cancer biology has been a matter of increasing
interest. Many patients with advanced cancer show high levels of neutrophilia, tumor …

Lung cancer is the leading cause of cancer death worldwide. Recent data suggest that
tumor-associated inflammatory cells may modify lung tumor growth and invasiveness,. To …

Accumulating evidence indicates that myeloid cells are critically involved in the
pathophysiology of human cancers. In contrast to the well-characterized tumor-associated …