Hepatocellular carcinoma is among the most lethal and prevalent cancers in the human
population. Despite its significance, there is only an elemental understanding of the …

Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

Hepatitis B virus X protein (HBx) has many cellular functions and is a major factor in hepatitis
and hepatocellular carcinoma caused by HBV infection. A proteomic approach was used to …

Chronic Hepatitis B Virus (HBV) infection is linked to hepatocellular carcinoma (HCC)
pathogenesis. Despite the availability of a HBV vaccine, current treatments for HCC are …

Hepatocarcinogenesis comprises of multiple, complex steps that occur after liver injury and
usually involve several pathways, including telomere dysfunction, cell cycle, WNT/β-catenin …

The HBx (X protein of hepatitis B virus) is a promiscuous transactivator implicated to play a
key role in hepatocellular carcinoma. However, HBx-regulated molecular events leading to …

Hepatitis B virus X protein (HBx) of the hepatitis B virus is strongly implicated in
angiogenesis and metastasis during hepatocarcinogenesis. Previously, we reported that …

Hepatitis B virus (HBV) X protein (HBx) is a viral regulatory and multifunctional protein. It is
well-known that the canonical HBx reading frame bears two phylogenetically conserved …

The multi‐factorial and multi‐step nature of cancer development makes analysis difficult in
cell culture and non‐genetic animal models. Recent progress in technology has allowed the …

Abstract Background/Aims: The hepatitis B virus X protein (HBx) is a viral trans-activator that
plays a crucial role in pathogenesis of hepatocellular carcinoma (HCC) via an unknown …