Computational methods for analysing multiscale 3D genome organization
Recent progress in whole-genome mapping and imaging technologies has enabled the
characterization of the spatial organization and folding of the genome in the nucleus. In …
characterization of the spatial organization and folding of the genome in the nucleus. In …
OpenNucleome for high-resolution nuclear structural and dynamical modeling
Z Lao, B Zhang - Biophysical Journal, 2024 - cell.com
The intricate structural organization of the human nucleus is fundamental to cellular function
and gene regulation. Recent advancements in experimental techniques, including high …
and gene regulation. Recent advancements in experimental techniques, including high …
Prediction of single-cell chromatin compartments from single-cell chromosome structures by MaxComp
Y Zhan, F Musella, F Alber - bioRxiv, 2024 - biorxiv.org
The genome is partitioned into distinct chromatin compartments with at least two main
classes, a transcriptionally active A and an inactive B compartment, corresponding mostly to …
classes, a transcriptionally active A and an inactive B compartment, corresponding mostly to …