The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …

MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

In humans, the monocyte pool comprises three subsets (classical, intermediate, and
nonclassical) that circulate in dynamic equilibrium. The kinetics underlying their generation …

Macrophages are endowed with a variety of receptors for lineage-determining growth
factors, T helper (Th) cell cytokines, and B cell, host, and microbial products. In tissues …

Monocytes and macrophages have crucial and distinct roles in tissue homeostasis and
immunity, but they also contribute to a broad spectrum of pathologies and are thus attractive …

Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …

Sepsis and trauma cause inflammation and elevated susceptibility to hospital-acquired
pneumonia. As phagocytosis by macrophages plays a critical role in the control of bacteria …

Inflammation is a biological response of the immune system to various insults, such as
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …

Currently, there is little evidence for a notable role of the vertebrate microRNA (miRNA)
system in the pathogenesis of RNA viruses. This is primarily attributed to the ease with which …

MicroRNAs (miRNAs) are small non-coding RNAs that play a wide variety of critical roles in
different biological processes by post-transcriptionally regulating gene expression. They …