Balanced general anesthesia, the most common management strategy used in anesthesia
care, entails the administration of different drugs together to create the anesthetic state …

Various theories for the neural basis of consciousness have been proposed, suggesting a
diversity of neural signs and mechanisms. We ask to what extent this diversity is real, or …

The widely used electroencephalogram-based indices for depth-of-anesthesia monitoring
assume that the same index value defines the same level of unconsciousness for all …

Oscillations are a prevalent feature of brain recordings. They are believed to play key roles
in neural communication and computation. Current analysis methods for studying neural …

Deep non-rapid eye movement sleep (NREM) and general anesthesia with propofol are
prominent states of reduced arousal linked to the occurrence of synchronized oscillations in …

At rest, the brain is traversed by spontaneous functional connectivity patterns. Two
hypotheses have been proposed for their origins: they may reflect a continuous stream of …

Neuroscience has made considerable progress in unraveling the neural correlates of mental
phenomena like self, consciousness, and perception. However, the “common currency” …

Unconsciousness is a fundamental component of general anesthesia (GA), but
anesthesiologists have no reliable ways to be certain that a patient is unconscious. To …

A common endpoint of general anesthetics is behavioral unresponsiveness [1], which is
commonly associated with loss of consciousness. However, subjects can become …

Background Anaesthetic drugs act at sites within the brain that undergo profound changes
during typical ageing. We postulated that anaesthesia-induced brain dynamics observed in …