[HTML][HTML] The role of functional amyloids in bacterial virulence

N Van Gerven, SE Van der Verren, DM Reiter… - Journal of molecular …, 2018 - Elsevier
Amyloid fibrils are best known as a product of human and animal protein misfolding
disorders, where amyloid formation is associated with cytotoxicity and disease. It is now …

Responses of cariogenic streptococci to environmental stresses

JAC Lemos, J Abranches, RA Burne - Current issues in molecular biology, 2005 - mdpi.com
To persist in the oral cavity, bacteria must be able to tolerate rapid and substantial
environmental fluctuations, particularly in pH and nutrient source and availability. Various …

The Biology of Streptococcus mutans

JA Lemos, SR Palmer, L Zeng, ZT Wen… - Microbiology …, 2019 - Am Soc Microbiol
As a major etiological agent of human dental caries, Streptococcus mutans resides primarily
in biofilms that form on the tooth surfaces, also known as dental plaque. In addition to caries …

Streptococcus mutans extracellular DNA is upregulated during growth in biofilms, actively released via membrane vesicles, and influenced by components of the …

S Liao, MI Klein, KP Heim, Y Fan, JP Bitoun… - Journal of …, 2014 - Am Soc Microbiol
Streptococcus mutans, a major etiological agent of human dental caries, lives primarily on
the tooth surface in biofilms. Limited information is available concerning the extracellular …

Glycosyltransferase-mediated biofilm matrix dynamics and virulence of Streptococcus mutans

K Rainey, SM Michalek, ZT Wen… - Applied and …, 2019 - Am Soc Microbiol
Streptococcus mutans is a key cariogenic bacterium responsible for the initiation of tooth
decay. Biofilm formation is a crucial virulence property. We discovered a putative …

Characteristics of Biofilm Formation by Streptococcus mutans in the Presence of Saliva

SJ Ahn, SJ Ahn, ZT Wen, LJ Brady… - Infection and …, 2008 - Am Soc Microbiol
Interactions between salivary agglutinin and the adhesin P1 of Streptococcus mutans
contribute to bacterial aggregation and mediate sucrose-independent adherence to tooth …

Curcumin reduces Streptococcus mutans biofilm formation by inhibiting sortase A activity

P Hu, P Huang, MW Chen - Archives of oral biology, 2013 - Elsevier
Background Sortase A is an enzyme responsible for the covalent attachment of Pac proteins
to the cell wall in Streptococcus mutans. It has been shown to play a role in modulating the …

Functional amyloid formation by Streptococcus mutans

MW Oli, HN Otoo, PJ Crowley, KP Heim… - …, 2012 - microbiologyresearch.org
Dental caries is a common infectious disease associated with acidogenic and aciduric
bacteria, including Streptococcus mutans. Organisms that cause cavities form recalcitrant …

Serotype classification of Streptococcus mutans and its detection outside the oral cavity

K Nakano, T Ooshima - Future microbiology, 2009 - Taylor & Francis
Streptococcus mutans, generally known as a major pathogen of dental caries, is also a
possible causative agent of bacteremia and infective endocarditis. S. mutans is classified …

Targeting of Streptococcus mutans Biofilms by a Novel Small Molecule Prevents Dental Caries and Preserves the Oral Microbiome

SS Garcia, MS Blackledge, S Michalek… - Journal of dental …, 2017 - journals.sagepub.com
Dental caries is a costly and prevalent disease characterized by the demineralization of the
tooth's enamel. Disease outcome is influenced by host factors, dietary intake, cariogenic …