Debiased machine learning for counterfactual survival functionals based on left-truncated right-censored data

ER Morenz, CJ Wolock, M Carone - arXiv preprint arXiv:2411.09017, 2024 - arxiv.org
Learning causal effects of a binary exposure on time-to-event endpoints can be challenging
because survival times may be partially observed due to censoring and systematically …

A surrogate endpoint based provisional approval causal roadmap

PB Gilbert, J Peng, L Han, T Lange, Y Lu, L Nie… - arXiv preprint arXiv …, 2024 - arxiv.org
For many rare diseases with no approved preventive interventions, promising interventions
exist, yet it has been difficult to conduct a pivotal phase 3 trial that could provide direct …

Nonparametric variable importance for time-to-event outcomes with application to prediction of HIV infection

CJ Wolock, PB Gilbert, N Simon, M Carone - arXiv preprint arXiv …, 2023 - arxiv.org
In survival analysis, complex machine learning algorithms have been increasingly used for
predictive modeling. Given a collection of features available for inclusion in a predictive …

Nonparametric methods for integration of survival analysis and machine learning

C Wolock - 2023 - search.proquest.com
This dissertation develops practical methodology incorporating modern machine learning
techniques into statistical inference, with a particular focus on the analysis of time-to-event …