Discovery of Novel Heterotricyclic Compounds as DNA-Dependent Protein Kinase (DNA-PK) Inhibitors with Enhanced Chemosensitivity, Oral Bioavailability, and the …
B Cheng, Y Shi, C Shao, S Wang, Z Su… - Journal of Medicinal …, 2024 - ACS Publications
In this work, a novel series of heterotricyclic DNA-PK inhibitors were rationally designed,
synthesized, and assessed for their biological activity. In the DNA-PK biochemical assay …
synthesized, and assessed for their biological activity. In the DNA-PK biochemical assay …
DNA Damage, DNA Repair, and Cancer
K Kuwahara - International Journal of Molecular Sciences, 2023 - pmc.ncbi.nlm.nih.gov
Following our first Special Issue, we are pleased to present this Special Issue in the
International Journal of Molecular Sciences, titled 'DNA Damage, DNA Repair, and Cancer …
International Journal of Molecular Sciences, titled 'DNA Damage, DNA Repair, and Cancer …
MEGA dPCR reveals chromosomal aberrations, NHEJ precise repair, recurrent nuclease cleavage and DSB half-life
N White, J Chalk, YT Hu, S Pins, P Antoniou… - 2024 - researchsquare.com
Advances in designer DNA editors, such as programmable nucleases, PASTE, Prime, and
base editors, have recently proved their therapeutic value and potential to treat genetic …
base editors, have recently proved their therapeutic value and potential to treat genetic …
Burzy nska, J.; Chmur, M. Does Reproductive Success in Natural and Anthropogenic Populations of Generalist Epipactis helleborine Depend on Flower Morphology …
E Brzosko, A Bajguz - Int. J. Mol. Sci - europepmc.org
The purpose of our study was to determine the role of flower structure and nectar
composition in shaping the reproductive success (RS) of the generalist orchid Epipactis …
composition in shaping the reproductive success (RS) of the generalist orchid Epipactis …