Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections

JMV Makabenta, A Nabawy, CH Li… - Nature Reviews …, 2021 - nature.com
Antibiotic-resistant bacterial infections arising from acquired resistance and/or through
biofilm formation necessitate the development of innovative 'outside of the box'therapeutics …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Antimicrobial peptides towards clinical application: Delivery and formulation

C Wang, T Hong, P Cui, J Wang, J Xia - Advanced drug delivery reviews, 2021 - Elsevier
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …

Antimicrobial peptide-based materials: Opportunities and challenges

A Rai, R Ferrão, P Palma, T Patricio… - Journal of Materials …, 2022 - pubs.rsc.org
The multifunctional properties of antimicrobial peptides (AMPs) make them attractive
candidates for the treatment of various diseases. AMPs are considered as alternatives to …

Self-assembling peptides as vectors for local drug delivery and tissue engineering applications

C Karavasili, DG Fatouros - Advanced drug delivery reviews, 2021 - Elsevier
Molecular self-assembly has forged a new era in the development of advanced biomaterials
for local drug delivery and tissue engineering applications. Given their innate …

Prospects of exploring the metal–organic framework for combating antimicrobial resistance

SA Polash, T Khare, V Kumar… - ACS Applied Bio …, 2021 - ACS Publications
Infectious diseases are a major public health concern globally. Infections caused by
pathogens with resistance against commonly used antimicrobial drugs or antibiotics (known …

Self-controllable proteinic antibacterial coating with bacteria-triggered antibiotic release for prevention of periprosthetic infection

HS Choi, J Yun, Y Jeong, YK Jo, HJ Cha - Biomaterials, 2024 - Elsevier
Periprosthetic infection is a devastating postimplantation complication in which a biofilm
layer harboring invasive microorganisms forms around orthopedic implants, leading to …

Alkaline-responsive polydiacetylene-peptide hydrogel for pH-sensing and on-demand antimicrobial release

W Chen, S Hazoor, R Madigan, AA Adones… - Materials Today …, 2022 - Elsevier
Antibiotic resistance is a global public health issue, accelerated by the misuse and overuse
of antibiotics. Microenvironment-targeted antimicrobial delivery is an emergent and …

Supramolecular peptide assemblies as antimicrobial scaffolds

AW Simonson, MR Aronson, SH Medina - Molecules, 2020 - mdpi.com
Antimicrobial discovery in the age of antibiotic resistance has demanded the prioritization of
non-conventional therapies that act on new targets or employ novel mechanisms. Among …

Host–guest interaction driven peptide assembly into photoresponsive two-dimensional nanosheets with switchable antibacterial activity

X Xie, B Gao, Z Ma, J Liu, J Zhang, J Liang… - CCS …, 2021 - chinesechemsoc.org
Selectively controlling the bioactivity of antimicrobial peptides is not only a fascinating
scientific challenge but also a necessity in localized antibacterial therapy. Here, a smart …