ERK/MAPK signalling in the developing brain: Perturbations and consequences
The extracellular regulated kinase/microtubule-associated protein kinase (ERK/MAPK)
signalling pathway transduces signals that cause an alteration in the ongoing metabolic …
signalling pathway transduces signals that cause an alteration in the ongoing metabolic …
Riding the crest to get a head: neural crest evolution in vertebrates
ML Martik, ME Bronner - Nature Reviews Neuroscience, 2021 - nature.com
In their seminal 1983 paper, Gans and Northcutt proposed that evolution of the vertebrate
'new head'was made possible by the advent of the neural crest and cranial placodes. The …
'new head'was made possible by the advent of the neural crest and cranial placodes. The …
Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment
Harnessing the potential of human embryonic stem cells to mimic normal and aberrant
development with standardized models is a pressing challenge. Here we use micropattern …
development with standardized models is a pressing challenge. Here we use micropattern …
scRNA-sequencing in chick suggests a probabilistic model for cell fate allocation at the neural plate border
AP Thiery, AL Buzzi, E Hamrud, C Cheshire… - Elife, 2023 - elifesciences.org
The vertebrate 'neural plate border'is a transient territory located at the edge of the neural
plate containing precursors for all ectodermal derivatives: the neural plate, neural crest …
plate containing precursors for all ectodermal derivatives: the neural plate, neural crest …
Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1
EK Stachowiak, CA Benson, ST Narla, A Dimitri… - Translational …, 2017 - nature.com
Studies of induced pluripotent stem cells (iPSCs) from schizophrenia patients and control
individuals revealed that the disorder is programmed at the preneuronal stage, involves a …
individuals revealed that the disorder is programmed at the preneuronal stage, involves a …
Regulatory logic underlying diversification of the neural crest
ML Martik, ME Bronner - Trends in Genetics, 2017 - cell.com
The neural crest is a transient, multipotent population of cells that arises at the border of the
developing nervous system. After closure of the neural tube, these cells undergo an …
developing nervous system. After closure of the neural tube, these cells undergo an …
Current perspectives of the signaling pathways directing neural crest induction
TJ Stuhlmiller, MI García-Castro - Cellular and Molecular Life Sciences, 2012 - Springer
The neural crest is a migratory population of embryonic cells with a tremendous potential to
differentiate and contribute to nearly every organ system in the adult body. Over the past two …
differentiate and contribute to nearly every organ system in the adult body. Over the past two …
WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate
Neural crest (NC) cells arise early in vertebrate development, migrate extensively and
contribute to a diverse array of ectodermal and mesenchymal derivatives. Previous models …
contribute to a diverse array of ectodermal and mesenchymal derivatives. Previous models …
[HTML][HTML] Setting appropriate boundaries: fate, patterning and competence at the neural plate border
The neural crest and craniofacial placodes are two distinct progenitor populations that arise
at the border of the vertebrate neural plate. This border region develops through a series of …
at the border of the vertebrate neural plate. This border region develops through a series of …
The neural border: Induction, specification and maturation of the territory that generates neural crest cells
P Pla, AH Monsoro-Burq - Developmental biology, 2018 - Elsevier
The neural crest is induced at the edge between the neural plate and the nonneural
ectoderm, in an area called the neural (plate) border, during gastrulation and neurulation. In …
ectoderm, in an area called the neural (plate) border, during gastrulation and neurulation. In …