[HTML][HTML] Bacteriophage communities are a reservoir of unexplored microbial diversity in neonatal health and disease

GR Young, A Nelson, CJ Stewart, DL Smith - Current Opinion in …, 2023 - Elsevier
Acquisition and development of the gut microbiome are vital for immune education in
neonates, especially those born preterm. As such, microbial communities have been …

Unveiling the pathogenic mechanisms of Clostridium perfringens toxins and virulence factors

A Camargo, JD Ramírez, R Kiu, LJ Hall… - Emerging Microbes & …, 2024 - Taylor & Francis
Clostridium perfringens causes multiple diseases in humans and animals. Its pathogenic
effect is supported by a broad and heterogeneous arsenal of toxins and other virulence …

Types A and F Clostridium perfringens in healthcare wastewater from Ghana

T Kawamura, I Prah, S Mahazu… - Applied and …, 2023 - Am Soc Microbiol
Clostridium perfringens can cause a plethora of diseases in humans and animals, making it
a growing public health concern. Insight into C. perfringens genomic studies has enhanced …

[HTML][HTML] Simulated digestions of free oligosaccharides and mucin-type O-glycans reveal a potential role for Clostridium perfringens

AG McDonald, F Lisacek - Scientific Reports, 2024 - nature.com
The development of a stable human gut microbiota occurs within the first year of life. Many
open questions remain about how microfloral species are influenced by the composition of …

[HTML][HTML] Superior performance of biofilm versus planktonic Limosilactobacillus reuteri in protection of the intestines and brain in a piglet model of necrotizing …

SJ Wala, N Sajankila, MV Ragan, AF Duff… - Scientific Reports, 2023 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal-related death in
premature infants. Its etiology is multifactorial, with intestinal dysbiosis playing a major role …

[HTML][HTML] shinyTempSignal: an R shiny application for exploring temporal and other phylogenetic signals

L Zhan, X Luo, W Xie, XA Zhu, Z Xie, J Lin, L Li… - Journal of Genetics and …, 2024 - Elsevier
The molecular clock model is fundamental for inferring species divergence times from
molecular sequences. However, its direct application may introduce significant biases due to …

Toxigenic Clostridium perfringens Isolated from At-Risk Paediatric Inflammatory Bowel Disease Patients

J Kuo, J Uzunovic, A Jacobson… - Journal of Crohn's …, 2024 - academic.oup.com
Abstract Background and Aims This study aimed to identify microbial drivers of inflammatory
bowel disease [IBD], by investigating mucosal-associated bacteria and their detrimental …

[HTML][HTML] Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways

X Tian, J Li, S Liu, Q Dong, Y Fu, R Luo, Y Sun, L Guo… - Heliyon, 2024 - cell.com
Poultry necrotic enteritis is an important enteric disease which might be controlled by
antibiotics. However, with the excessive use of antibiotics, the phenomenon of drug …

Cannabidiol improves the cognitive function of SAMP8 AD model mice involving the microbiota-gut-brain axis

BQ Ma, JX Jia, H Wang, SJ Li, ZJ Yang… - Journal of Toxicology …, 2024 - Taylor & Francis
Cannabidiol (CBD), a natural component extracted from Cannabis sativa L. exerts
neuroprotective, antioxidant, and anti-inflammatory effects in Alzheimer's disease (AD), a …

Bacterial cholesterol-dependent cytolysins and their interaction with the human immune response

TC Sanford, RK Tweten… - Current Opinion in …, 2024 - journals.lww.com
This review provides new information on how CDCs alter host immune responses to aid
bacteria in pathogenesis. These studies can assist in the design of more efficient vaccines …