Ante mortem diagnosis of tuberculosis in cattle: a review of the tuberculin tests, γ-interferon assay and other ancillary diagnostic techniques

R De la Rua-Domenech, AT Goodchild… - Research in veterinary …, 2006 - Elsevier
The early, preclinical stages of bovine TB can be detected in live animals by the use of tests
of cellular immunity (the skin, γ-interferon and lymphocyte transformation tests). Tests of …

Bovine tuberculosis: a review of current and emerging diagnostic techniques in view of their relevance for disease control and eradication

I Schiller, B Oesch, HM Vordermeier… - Transboundary and …, 2010 - Wiley Online Library
Existing strategies for long‐term bovine tuberculosis (bTB) control/eradication campaigns
are being reconsidered in many countries because of the development of new testing …

BOVIGAMTM: an in vitro cellular diagnostic test for bovine tuberculosis

PR Wood, SL Jones - Tuberculosis, 2001 - Elsevier
BOVIGAMTMwhich is based on the detection of gamma interferon (IFN-γ) is a rapid,
laboratory assay of a cell mediated immune response that may be used for the detection of …

Diagnosis of Mycobacterium bovis infection in cattle by use of the gamma-interferon (Bovigam®) assay

E Gormley, MB Doyle, T Fitzsimons, K McGill… - Veterinary …, 2006 - Elsevier
The strategic use of the gamma-interferon (IFN-γ) assay (Bovigam®) can provide a means
for the early identification of Mycobacterium bovis infected cattle, thus ensuring their removal …

Cattle-to-cattle transmission of Mycobacterium bovis

AV Goodchild, RS Clifton-Hadley - Tuberculosis, 2001 - Elsevier
This review, illustrated with data on the characteristics of herds infected with Mycobacterium
bovis (TB) in Great Britain (GB), attempts to identify the role of cattle-to-cattle transmission …

An evaluation of the gamma interferon test for detecting bovine tuberculosis in cattle 8 to 28 days after tuberculin skin testing

TJ Ryan, BM Buddle, GW De Lisle - Research in veterinary science, 2000 - Elsevier
The gamma interferon (IFN-γ) test was evaluated for its ability to diagnose bovine
tuberculosis in cattle that 8 to 28 days previously had a positive caudal fold skin test. The …

Using latent class analysis to estimate the test characteristics of the γ-interferon test, the single intradermal comparative tuberculin test and a multiplex immunoassay …

TA Clegg, A Duignan, C Whelan, E Gormley… - Veterinary …, 2011 - Elsevier
Considerable effort has been devoted to improving the existing diagnostic tests for bovine
tuberculosis (single intradermal comparative tuberculin test [SICTT] and γ-interferon assay [γ …

[HTML][HTML] Repeat tuberculin skin testing leads to desensitisation in naturally infected tuberculous cattle which is associated with elevated interleukin-10 and decreased …

M Coad, D Clifford, SG Rhodes, RG Hewinson… - Veterinary …, 2010 - ncbi.nlm.nih.gov
The principal surveillance tool used to control bovine tuberculosis in cattle is the removal of
animals that provide a positive response to the tuberculin skin-test. In this study we …

Diversity of antigen recognition by serum antibodies in experimental bovine tuberculosis

KP Lyashchenko, JM Pollock, R Colangeli… - Infection and …, 1998 - Am Soc Microbiol
Tuberculosis in cattle remains a major zoonotic and economic problem in many countries.
The standard diagnostic assay for bovine tuberculosis, the intradermal tuberculin test, has …

The effect of the tuberculin test and the consequences of a delay in blood culture on the sensitivity of a gamma-interferon assay for the detection of Mycobacterium …

E Gormley, MB Doyle, K McGill, E Costello… - Veterinary immunology …, 2004 - Elsevier
The strategic use of the gamma-interferon (IFN-γ) assay (Bovigam®) can provide a means
for the early identification of Mycobacterium bovis infected cattle, thus ensuring their removal …