The growing field of immunometabolism has taught us how metabolic cellular reactions and
processes not only provide a means to generate ATP and biosynthetic precursors, but are …

All metazoans that utilize molecular oxygen (O2) for metabolic purposes have the capacity to
adapt to hypoxia, the condition that arises when O2 demand exceeds supply. This is …

Cellular senescence is a state of stable proliferative arrest triggered by damaging signals.
Senescent cells persist during aging and promote age-related pathologies via the pro …

Hypoxia inducible factors (HIFs) are α/β heterodimeric transcription factors that direct
multiple cellular and systemic responses in response to changes in oxygen availability. The …

Iron is required for efficient oxygen transport, and hypoxia signaling links erythropoiesis with
iron homeostasis. Hypoxia induces a highly conserved signaling pathway in cells under …

Additive manufacturing of porous, open-cellular metal or alloy implants, fabricated by laser
or electron beam melting of a powder bed, is briefly reviewed in relation to optimizing …

Disorders characterized by ischemia/reperfusion (I/R) are the most common causes of
debilitating diseases and death in stroke, cardiovascular ischemia, acute kidney injury or …

Ayurveda, an ancient Indian system of medicine documented and practised since 1500 BC,
follows a systems approach that has interesting parallels with contemporary personalized …

The pandemic rise in obesity has resulted in an increased incidence of metabolic
complications. Non-alcoholic fatty liver disease is the hepatic manifestation of the metabolic …

Wound healing responses are physiological reactions to injuries and share common
characteristics and phases independently of the injured organ or tissue. A major hallmark of …