Neutrophils as potential therapeutic targets in hepatocellular carcinoma
The success of atezolizumab plus bevacizumab treatment contributed to a shift in systemic
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …
Tumor associated neutrophils. Their role in tumorigenesis, metastasis, prognosis and therapy
MT Masucci, M Minopoli, MV Carriero - Frontiers in oncology, 2019 - frontiersin.org
Tumor Associated Neutrophils (TANs) are engaged into the tumor microenvironment by
cytokines and chemokines, can be distinguished according to their activation and cytokine …
cytokines and chemokines, can be distinguished according to their activation and cytokine …
Tumour-associated neutrophils in patients with cancer
ME Shaul, ZG Fridlender - Nature reviews Clinical oncology, 2019 - nature.com
The role and importance of neutrophils in cancer has become increasingly apparent over
the past decade. Neutrophils accumulate in the peripheral blood of patients with cancer …
the past decade. Neutrophils accumulate in the peripheral blood of patients with cancer …
Tumor-infiltrating lymphocytes and their prognostic value in cutaneous melanoma
F Maibach, H Sadozai, SM Seyed Jafari… - Frontiers in …, 2020 - frontiersin.org
Recent breakthroughs in tumor immunotherapy such as immune checkpoint blockade (ICB)
antibodies, have demonstrated the capacity of the immune system to fight cancer in a …
antibodies, have demonstrated the capacity of the immune system to fight cancer in a …
Neutrophils in cancer: neutral no more
Neutrophils are indispensable antagonists of microbial infection and facilitators of wound
healing. In the cancer setting, a newfound appreciation for neutrophils has come into view …
healing. In the cancer setting, a newfound appreciation for neutrophils has come into view …
The role of myeloid cells in cancer therapies
Recent clinical trials have demonstrated the ability to durably control cancer in some
patients by manipulating T lymphocytes. These immunotherapies are revolutionizing cancer …
patients by manipulating T lymphocytes. These immunotherapies are revolutionizing cancer …
Neutrophils in the tumor microenvironment
DR Powell, A Huttenlocher - Trends in immunology, 2016 - cell.com
Neutrophils are the first responders to sites of acute tissue damage and infection. Recent
studies suggest that in addition to neutrophil apoptosis, resolution of neutrophil inflammation …
studies suggest that in addition to neutrophil apoptosis, resolution of neutrophil inflammation …
Development and validation of an individualized immune prognostic signature in early-stage nonsquamous non–small cell lung cancer
Importance The prevalence of early-stage non–small cell lung cancer (NSCLC) is expected
to increase with recent implementation of annual screening programs. Reliable prognostic …
to increase with recent implementation of annual screening programs. Reliable prognostic …
Neutrophils and PMN-MDSC: Their biological role and interaction with stromal cells
J Zhou, Y Nefedova, A Lei, D Gabrilovich - Seminars in immunology, 2018 - Elsevier
Neutrophils and polymorphonucler myeloid-derived suppressor cells (PMN-MDSC) share
origin and many morphological and phenotypic features. However, they have different …
origin and many morphological and phenotypic features. However, they have different …
Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer
EB Eruslanov, PS Bhojnagarwala… - The Journal of …, 2014 - Am Soc Clin Investig
Infiltrating inflammatory cells are highly prevalent within the tumor microenvironment and
mediate many processes associated with tumor progression; however, the contribution of …
mediate many processes associated with tumor progression; however, the contribution of …