Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Metabolite concentration changes in humans after a bout of exercise: a systematic review of exercise metabolomics studies

D Schranner, G Kastenmüller, M Schönfelder… - Sports medicine …, 2020 - Springer
Background Exercise changes the concentrations of many metabolites, which are small
molecules (< 1.5 kDa) metabolized by the reactions of human metabolism. In recent years …

The regulation of fat metabolism during aerobic exercise

A Muscella, E Stefàno, P Lunetti, L Capobianco… - Biomolecules, 2020 - mdpi.com
Since the lipid profile is altered by physical activity, the study of lipid metabolism is a
remarkable element in understanding if and how physical activity affects the health of both …

Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

B Walitt, K Singh, SR LaMunion, M Hallett… - Nature …, 2024 - nature.com
Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a
disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is …

Time of exercise specifies the impact on muscle metabolic pathways and systemic energy homeostasis

S Sato, AL Basse, M Schönke, S Chen, M Samad… - Cell metabolism, 2019 - cell.com
While the timing of food intake is important, it is unclear whether the effects of exercise on
energy metabolism are restricted to unique time windows. As circadian regulation is key to …

Understanding the female athlete: molecular mechanisms underpinning menstrual phase differences in exercise metabolism

T Oosthuyse, JA Strauss, AC Hackney - European Journal of Applied …, 2023 - Springer
Research should equitably reflect responses in men and women. Including women in
research, however, necessitates an understanding of the ovarian hormones and menstrual …

Tuning fatty acid oxidation in skeletal muscle with dietary fat and exercise

AM Fritzen, AM Lundsgaard, B Kiens - Nature Reviews Endocrinology, 2020 - nature.com
Both the consumption of a diet rich in fatty acids and exercise training result in similar
adaptations in several skeletal muscle proteins. These adaptations are involved in fatty acid …

Serine catabolism feeds NADH when respiration is impaired

L Yang, JCG Canaveras, Z Chen, L Wang, L Liang… - Cell metabolism, 2020 - cell.com
NADH provides electrons for aerobic ATP production. In cells deprived of oxygen or with
impaired electron transport chain activity, NADH accumulation can be toxic. To minimize …

Interactions between insulin and exercise

EA Richter, L Sylow, M Hargreaves - Biochemical journal, 2021 - portlandpress.com
The interaction between insulin and exercise is an example of balancing and modifying the
effects of two opposing metabolic regulatory forces under varying conditions. While insulin is …

[HTML][HTML] Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

Q Ouyang, Q Chen, S Ke, L Ding, X Yang, P Rong… - Developmental Cell, 2023 - cell.com
Dynamic interaction between lipid droplets (LDs) and mitochondria controls the mobilization
of long-chain fatty acids (LCFAs) from LDs for mitochondrial β-oxidation in skeletal muscle in …