Context.—Rhabdomyosarcomas comprise a relatively common diagnostic entity among
childhood cancers and a relatively rare one among adult tumors. They may possess a …

In this review we examine the diagnosis and treatment of pediatric liver tumors-both
malignant and benign. The two most common malignant tumors are hepatoblastoma and …

Malignant primary hepatic tumors in children include lesions unique to the pediatric age
group and others that are more common in adults. Important considerations when evaluating …

Rhabdomyosarcoma (RMS) is a mesenchymal malignancy composed of neoplastic primitive
precursor cells that exhibit histological features of myogenic differentiation. Despite intensive …

Fusion-positive rhabdomyosarcoma (FP-RMS) driven by the expression of the PAX3-FOXO1
(P3F) fusion oncoprotein is an aggressive subtype of pediatric rhabdomyosarcoma. FP-RMS …

This article aims to give an overview of pediatric liver tumors; in particular of the two most
frequently occurring groups of hepatoblastomas and hepatocellular carcinomas. Focus lays …

Liver tumors in childhood are rare. Approximately two-thirds of all pediatric liver tumors are
malignant, including hepatoblastoma (HB; 37%), hepatocellular carcinoma (HCC; 21%), and …

Rhabdomyosarcoma (RMS) is an aggressive skeletal muscle-lineage tumor composed of
malignant myoblasts that fail to exit the cell cycle and are blocked from fusing into syncytial …

Alveolar rhabdomyosarcoma (ARMS) is a pediatric sarcoma that typically occurs in older
children predominantly arising in the trunk and extremities, and exhibits a worse prognosis …

Abstract The Children's Oncology Group (COG) uses Clinical Group (CG) and modified
Tumor Node Metastasis (TNM) stage to classify rhabdomyosarcoma (RMS). CG is based on …