Amongst the natural polymers, chitin is the second most abundant, present mainly in fungi
and exoskeleton of crustaceans. It forms a major part of the seafood waste as compiled and …

Chitosan-based nanomaterials have attracted significant attention in the biomedical field
because of their unique biodegradable, biocompatible, non-toxic, and antimicrobial nature …

The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Protein/antibody therapeutics have exhibited the advantages of high specificity and activity
even at an extremely low concentration compared to small molecule drugs. However, they …

The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …

It is well known that the central nervous system (CNS) has a limited regenerative capacity
and that many therapeutic molecules cannot cross the blood brain barrier (BBB). The use of …

Numerous drugs have emerged to treat various diseases, such as COVID-19, cancer, and
protect human health. Approximately 40% of them are lipophilic and are used for treating …

Currently, Alzheimer's disease (AD) accounts for more than half of all dementia cases.
Although genetics, age, and environmental factors affect the disease, the cause of AD is not …

We designed a delivery system to obtain an efficient and optimal nose-to-brain transport of
BACE1 siRNA, potentially useful in the treatment of Alzheimer's disease. We selected a cell …

Epileptic seizures and anxiety crisis are severe conditions that require fast and effective
treatment, targeting the brain. Current emergency antiepiletics and anxiolytics have limited …